4690


Homo sapiens (NCBI)

Features
Gene ID: 4690
  
Biological name :
  
Synonyms : NCK1 / NCK adaptor protein 1 / NCK|NCKalpha|nck-1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204725_s_at (Human Genome U133 Plus 2.0 Array)   211063_s_at (Human Genome U133 Plus 2.0 Array)   229895_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1370484228
RefSeq - 299829184
RefSeq - 5453754
RefSeq - 635172876
RefSeq - NC_000003.12
RefSeq - NP_001177725.1
RefSeq - NP_001278928.1
RefSeq - NP_006144.1
RefSeq - XP_024309306.1
RefSeq - NM_001190796.2
RefSeq - NM_001291999.1
RefSeq - NM_006153.5
RefSeq - XM_024453538.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000158092 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0006930 substrate-dependent cell migration, cell extension IEA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007172 signal complex assembly NAS
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IMP
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0036493 positive regulation of translation in response to endoplasmic reticulum stress IDA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042102 positive regulation of T cell proliferation IMP
 biological_processGO:0042110 T cell activation IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IMP
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051707 response to other organism IEA
 biological_processGO:0060548 negative regulation of cell death IDA
 biological_processGO:0070262 peptidyl-serine dephosphorylation IDA
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:1903676 positive regulation of cap-dependent translational initiation IDA
 biological_processGO:1903679 positive regulation of cap-independent translational initiation IDA
 biological_processGO:1903898 negative regulation of PERK-mediated unfolded protein response IDA
 biological_processGO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IDA
 biological_processGO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IDA
 cellular_componentGO:0000164 protein phosphatase type 1 complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0012506 vesicle membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IDA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity NAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008093 cytoskeletal adaptor activity NAS
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030159 receptor signaling complex scaffold activity NAS
 molecular_functionGO:0030674 protein binding, bridging IC
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0046875 ephrin receptor binding IEA
 molecular_functionGO:0060090 molecular adaptor activity IPI
 molecular_functionGO:0071074 eukaryotic initiation factor eIF2 binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr