4791


Homo sapiens (NCBI)
rnapolymeraseiiactivityregulationbindingnf-kappabfactorsequence-specificdnaproximalpromoterfolliculardendriticcelldifferentiationgerminalcenterformationdna-templatedagingextracellularmatrixorganizationtypeinterferonproductionresponselipopolysaccharide

Features
Gene ID: 4791
  
Biological name :
  
Synonyms : CVID10|H2TF1|LYT-10|LYT10|NF-kB2|p100|p49/p100|p52 / NFKB2 / nuclear factor kappa B subunit 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207535_s_at (Human Genome U133 Plus 2.0 Array)   209636_at (Human Genome U133 Plus 2.0 Array)   211524_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1018443262
RefSeq - 1019366640
RefSeq - 1034568335
RefSeq - 117320527
RefSeq - 117320531
RefSeq - 1370457169
RefSeq - 1370457172
RefSeq - 387157878
RefSeq - 570359559
RefSeq - 767962963
RefSeq - 767962965
RefSeq - NC_000010.11
RefSeq - NG_033874.1
RefSeq - NP_001070962.1
RefSeq - NP_001248332.1
RefSeq - NP_001275653.1
RefSeq - NP_001309863.1
RefSeq - NP_001309864.1
RefSeq - NP_002493.3
RefSeq - XP_011538132.1
RefSeq - XP_011538133.1
RefSeq - XP_016871767.1
RefSeq - XP_024303794.1
RefSeq - XP_024303795.1
RefSeq - NM_001077494.3
RefSeq - NM_001261403.2
RefSeq - NM_001288724.1
RefSeq - NM_001322934.1
RefSeq - NM_001322935.1
RefSeq - NM_002502.5
RefSeq - XM_024448027.1
RefSeq - XM_011539830.3
RefSeq - XM_011539831.2
RefSeq - XM_017016278.1
RefSeq - XM_024448026.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000077150 to get all the annotations available for this gene.


Gene Ontology (GO)
cellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellular developmental processcell activationimmune responseanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processagingcellular component organizationcytokine productionresponse to external stimulusresponse to chemicalresponse to biotic stimuluscell communicationcellular response to stimulusregulation of molecular functioncellulacellular developmental processcell accell activationimmune immune responseanatomianatomical structure developmentnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processagingagingcellulacellular component organizationcytokincytokine productionresponsresponse to external stimulusresponsresponse to chemicalresponsresponse to biotic stimuluscell cocell communicationcellulacellular response to stimulusregulatregulation of molecular function
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound bindingDNA-binding transcription faDNA-binding transcription factor activitytranscription coregulator actranscription coregulator activityprotein bindingprotein binding
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0002268 follicular dendritic cell differentiation IEA
 biological_processGO:0002467 germinal center formation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0038061 NIK/NF-kappaB signaling TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0033257 Bcl3/NF-kappaB2 complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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