4842


Homo sapiens (NCBI)

Features
Gene ID: 4842
  
Biological name :
  
Synonyms : IHPS1|N-NOS|NC-NOS|NOS|bNOS|nNOS / nitric oxide synthase 1 / NOS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1560974_s_at (Human Genome U133 Plus 2.0 Array)   207309_at (Human Genome U133 Plus 2.0 Array)   207310_s_at (Human Genome U133 Plus 2.0 Array)   231916_at (Human Genome U133 Plus 2.0 Array)   239132_at (Human Genome U133 Plus 2.0 Array)   240911_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10835173
RefSeq - 323635431
RefSeq - 323635434
RefSeq - 323635436
RefSeq - NC_000012.12
RefSeq - NG_011991.2
RefSeq - NP_000611.1
RefSeq - NP_001191142.1
RefSeq - NP_001191143.1
RefSeq - NP_001191147.1
RefSeq - NM_000620.4
RefSeq - NM_001204213.1
RefSeq - NM_001204214.1
RefSeq - NM_001204218.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000089250 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEP
 biological_processGO:0002028 regulation of sodium ion transport ISS
 biological_processGO:0006527 arginine catabolic process IC
 biological_processGO:0006809 nitric oxide biosynthetic process ISS
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0006941 striated muscle contraction ISS
 biological_processGO:0007263 nitric oxide mediated signal transduction IBA
 biological_processGO:0007520 myoblast fusion TAS
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010523 negative regulation of calcium ion transport into cytosol TAS
 biological_processGO:0018119 peptidyl-cysteine S-nitrosylation ISS
 biological_processGO:0031284 positive regulation of guanylate cyclase activity IBA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033555 multicellular organismal response to stress IMP
 biological_processGO:0035066 positive regulation of histone acetylation ISS
 biological_processGO:0042136 neurotransmitter biosynthetic process TAS
 biological_processGO:0042311 vasodilation IMP
 biological_processGO:0042738 exogenous drug catabolic process ISS
 biological_processGO:0043267 negative regulation of potassium ion transport ISS
 biological_processGO:0045454 cell redox homeostasis TAS
 biological_processGO:0045776 negative regulation of blood pressure IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0051346 negative regulation of hydrolase activity ISS
 biological_processGO:0051612 negative regulation of serotonin uptake ISS
 biological_processGO:0051926 negative regulation of calcium ion transport ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0055117 regulation of cardiac muscle contraction TAS
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity TAS
 biological_processGO:0071363 cellular response to growth factor stimulus ISS
 biological_processGO:0098735 positive regulation of the force of heart contraction ISS
 biological_processGO:0098924 retrograde trans-synaptic signaling by nitric oxide IEA
 biological_processGO:0140196 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process IEA
 biological_processGO:1902307 positive regulation of sodium ion transmembrane transport ISS
 biological_processGO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel TAS
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0001917 photoreceptor inner segment ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton ISS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0012506 vesicle membrane IBA
 cellular_componentGO:0014069 postsynaptic density IBA
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0032991 protein-containing complex ISS
 cellular_componentGO:0042383 sarcolemma IDA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045121 membrane raft ISS
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:1990425 ryanodine receptor complex TAS
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IBA
 molecular_functionGO:0004517 nitric-oxide synthase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0010181 FMN binding ISS
 molecular_functionGO:0016491 oxidoreductase activity IBA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IBA
 molecular_functionGO:0017080 sodium channel regulator activity ISS
 molecular_functionGO:0020037 heme binding ISS
 molecular_functionGO:0034617 tetrahydrobiopterin binding NAS
 molecular_functionGO:0034618 arginine binding TAS
 molecular_functionGO:0044325 ion channel binding TAS
 molecular_functionGO:0046870 cadmium ion binding ISS
 molecular_functionGO:0050660 flavin adenine dinucleotide binding ISS
 molecular_functionGO:0050661 NADP binding ISS
 molecular_functionGO:0097110 scaffold protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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