4846


Homo sapiens (NCBI)

Features
Gene ID: 4846
  
Biological name :
  
Synonyms : ECNOS|eNOS / nitric oxide synthase 3 / NOS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205581_s_at (Human Genome U133 Plus 2.0 Array)   229093_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 231571314
RefSeq - 231571329
RefSeq - 231571356
RefSeq - 40254422
RefSeq - NC_000007.14
RefSeq - NG_011992.1
RefSeq - NP_000594.2
RefSeq - NP_001153581.1
RefSeq - NP_001153582.1
RefSeq - NP_001153583.1
RefSeq - NM_000603.4
RefSeq - NM_001160109.1
RefSeq - NM_001160110.1
RefSeq - NM_001160111.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164867 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001542 ovulation from ovarian follicle IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001974 blood vessel remodeling ISS
 biological_processGO:0002028 regulation of sodium ion transport IEA
 biological_processGO:0003057 regulation of the force of heart contraction by chemical signal IEA
 biological_processGO:0003100 regulation of systemic arterial blood pressure by endothelin IMP
 biological_processGO:0003180 aortic valve morphogenesis ISS
 biological_processGO:0003184 pulmonary valve morphogenesis ISS
 biological_processGO:0003203 endocardial cushion morphogenesis ISS
 biological_processGO:0006527 arginine catabolic process IDA
 biological_processGO:0006809 nitric oxide biosynthetic process IDA
 biological_processGO:0007005 mitochondrion organization ISS
 biological_processGO:0007263 nitric oxide mediated signal transduction IBA
 biological_processGO:0008217 regulation of blood pressure NAS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0009408 response to heat NAS
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010544 negative regulation of platelet activation NAS
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0014740 negative regulation of muscle hyperplasia ISS
 biological_processGO:0014806 smooth muscle hyperplasia ISS
 biological_processGO:0019430 removal of superoxide radicals IDA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0031284 positive regulation of guanylate cyclase activity ISS
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0034405 response to fluid shear stress IEP
 biological_processGO:0042311 vasodilation NAS
 biological_processGO:0043267 negative regulation of potassium ion transport IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0043542 endothelial cell migration IMP
 biological_processGO:0045454 cell redox homeostasis TAS
 biological_processGO:0045766 positive regulation of angiogenesis ISS
 biological_processGO:0045776 negative regulation of blood pressure IBA
 biological_processGO:0048873 homeostasis of number of cells within a tissue ISS
 biological_processGO:0050880 regulation of blood vessel size ISS
 biological_processGO:0050999 regulation of nitric-oxide synthase activity TAS
 biological_processGO:0051186 cofactor metabolic process TAS
 biological_processGO:0051346 negative regulation of hydrolase activity IEA
 biological_processGO:0051926 negative regulation of calcium ion transport IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0070168 negative regulation of biomineral tissue development ISS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors ISS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005623 cell ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0012506 vesicle membrane IBA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 molecular_functionGO:0003785 actin monomer binding IPI
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IBA
 molecular_functionGO:0004517 nitric-oxide synthase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0010181 FMN binding NAS
 molecular_functionGO:0016491 oxidoreductase activity IBA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IBA
 molecular_functionGO:0020037 heme binding IDA
 molecular_functionGO:0034617 tetrahydrobiopterin binding IDA
 molecular_functionGO:0034618 arginine binding IDA
 molecular_functionGO:0046870 cadmium ion binding NAS
 molecular_functionGO:0050660 flavin adenine dinucleotide binding NAS
 molecular_functionGO:0050661 NADP binding NAS
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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