4864


Homo sapiens (NCBI)

Features
Gene ID: 4864
  
Biological name :
  
Synonyms : NPC1 / NPC intracellular cholesterol transporter 1 / NPC|POGZ|SLC65A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202679_at (Human Genome U133 Plus 2.0 Array)   217584_at (Human Genome U133 Plus 2.0 Array)   238568_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034604107
RefSeq - 1034604110
RefSeq - 1034604112
RefSeq - 1034604114
RefSeq - 255652944
RefSeq - 530413812
RefSeq - 530413814
RefSeq - 530413816
RefSeq - 578832534
RefSeq - NC_000018.10
RefSeq - NG_012795.1
RefSeq - NP_000262.2
RefSeq - XP_005258334.1
RefSeq - XP_005258335.1
RefSeq - XP_005258336.1
RefSeq - XP_006722542.1
RefSeq - XP_016881273.1
RefSeq - XP_016881274.1
RefSeq - XP_016881275.1
RefSeq - XP_016881276.1
RefSeq - NM_000271.4
RefSeq - XM_017025787.1
RefSeq - XM_005258277.1
RefSeq - XM_005258278.5
RefSeq - XM_005258279.2
RefSeq - XM_006722479.3
RefSeq - XM_017025784.1
RefSeq - XM_017025785.1
RefSeq - XM_017025786.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000141458 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IDA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006914 autophagy IGI
 biological_processGO:0007041 lysosomal transport ISS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0008206 bile acid metabolic process ISS
 biological_processGO:0016242 negative regulation of macroautophagy IEA
 biological_processGO:0030301 cholesterol transport IDA
 biological_processGO:0031579 membrane raft organization IMP
 biological_processGO:0033344 cholesterol efflux IDA
 biological_processGO:0034383 low-density lipoprotein particle clearance TAS
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042632 cholesterol homeostasis ISS
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0046718 viral entry into host cell IMP
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IEA
 biological_processGO:0090150 establishment of protein localization to membrane IDA
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015248 sterol transporter activity TAS
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0038023 signaling receptor activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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