4976


Homo sapiens (NCBI)

Features
Gene ID: 4976
  
Biological name :
  
Synonyms : BERHS|MGM1|MTDPS14|NPG|NTG|largeG / OPA1 / OPA1, mitochondrial dynamin like GTPase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212213_x_at (Human Genome U133 Plus 2.0 Array)   212214_at (Human Genome U133 Plus 2.0 Array)   214306_at (Human Genome U133 Plus 2.0 Array)   241027_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001341592.1
RefSeq - NP_001341593.1
RefSeq - NP_056375.2
RefSeq - NP_570844.1
RefSeq - NP_570845.1
RefSeq - NP_570846.1
RefSeq - NP_570847.2
RefSeq - NP_570848.1
RefSeq - NP_570849.2
RefSeq - NP_570850.2
RefSeq - NG_011605.1
RefSeq - 1233267517
RefSeq - 1241781413
RefSeq - 18860831
RefSeq - 18860833
RefSeq - 18860835
RefSeq - 18860841
RefSeq - 224831243
RefSeq - 224831248
RefSeq - 224831251
RefSeq - 224831253
RefSeq - NC_000003.12
RefSeq - XR_001740159.2
RefSeq - NM_001354663.1
RefSeq - NM_001354664.1
RefSeq - NM_015560.2
RefSeq - NM_130831.2
RefSeq - NM_130832.2
RefSeq - NM_130833.2
RefSeq - NM_130834.2
RefSeq - NM_130835.2
RefSeq - NM_130836.2
RefSeq - NM_130837.2
RefSeq - XR_001740158.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198836 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000002 mitochondrial genome maintenance IMP
 biological_processGO:0000266 mitochondrial fission TAS
 biological_processGO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007005 mitochondrion organization NAS
 biological_processGO:0007007 inner mitochondrial membrane organization IDA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0008053 mitochondrial fusion TAS
 biological_processGO:0010636 positive regulation of mitochondrial fusion IEA
 biological_processGO:0014042 positive regulation of neuron maturation IEA
 biological_processGO:0014850 response to muscle activity IEA
 biological_processGO:0019896 axonal transport of mitochondrion TAS
 biological_processGO:0036444 calcium import into the mitochondrion IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0046039 GTP metabolic process IDA
 biological_processGO:0048285 organelle fission IBA
 biological_processGO:0048312 intracellular distribution of mitochondria IEA
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0061003 positive regulation of dendritic spine morphogenesis IEA
 biological_processGO:0061025 membrane fusion IBA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0090102 cochlea development IEA
 biological_processGO:0090201 negative regulation of release of cytochrome c from mitochondria IMP
 biological_processGO:0090398 cellular senescence IDA
 biological_processGO:0097749 membrane tubulation IDA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
 biological_processGO:1904643 response to curcumin IEA
 biological_processGO:1905232 cellular response to L-glutamate IEA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IDA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005758 mitochondrial intermembrane space ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030061 mitochondrial crista IDA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031314 extrinsic component of mitochondrial inner membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0000287 magnesium ion binding NAS
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0070300 phosphatidic acid binding IDA
 molecular_functionGO:1901612 cardiolipin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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