5025


Homo sapiens (NCBI)

Features
Gene ID: 5025
  
Biological name :
  
Synonyms : P2RX4 / P2X4|P2X4R / purinergic receptor P2X 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204088_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 28416927
RefSeq - 378404897
RefSeq - 386869358
RefSeq - 386869362
RefSeq - 767974435
RefSeq - NC_000012.12
RefSeq - NP_001243725.1
RefSeq - NP_001248326.1
RefSeq - NP_001248327.1
RefSeq - NP_002551.2
RefSeq - XP_011536718.1
RefSeq - NM_175568.1
RefSeq - XR_001748726.2
RefSeq - XR_001748727.1
RefSeq - XR_001748728.1
RefSeq - XR_001748729.2
RefSeq - NR_046372.1
RefSeq - NR_046373.1
RefSeq - XM_011538416.2
RefSeq - XR_944559.2
RefSeq - NM_001256796.1
RefSeq - NM_001261397.1
RefSeq - NM_001261398.1
RefSeq - NM_002560.2
RefSeq - NM_175567.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000135124 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001894 tissue homeostasis NAS
 biological_processGO:0002028 regulation of sodium ion transport ISS
 biological_processGO:0006812 cation transport IBA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008217 regulation of blood pressure IMP
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol IMP
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0019228 neuronal action potential IEA
 biological_processGO:0019233 sensory perception of pain ISS
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0032308 positive regulation of prostaglandin secretion NAS
 biological_processGO:0033198 response to ATP IDA
 biological_processGO:0034220 ion transmembrane transport IDA
 biological_processGO:0034405 response to fluid shear stress IDA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IMP
 biological_processGO:0042118 endothelial cell activation TAS
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IMP
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process NAS
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IMP
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051899 membrane depolarization IDA
 biological_processGO:0051928 positive regulation of calcium ion transport NAS
 biological_processGO:0055117 regulation of cardiac muscle contraction IMP
 biological_processGO:0055119 relaxation of cardiac muscle IMP
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0070588 calcium ion transmembrane transport IDA
 biological_processGO:0071294 cellular response to zinc ion ISS
 biological_processGO:0071318 cellular response to ATP IDA
 biological_processGO:0097190 apoptotic signaling pathway IDA
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis IMP
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IMP
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IDA
 molecular_functionGO:0005102 signaling receptor binding ISS
 molecular_functionGO:0005507 copper ion binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IC
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0035381 ATP-gated ion channel activity IBA
 molecular_functionGO:0042803 protein homodimerization activity NAS
 molecular_functionGO:0045296 cadherin binding IPI
 molecular_functionGO:0099604 ligand-gated calcium channel activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr