5045


Homo sapiens (NCBI)

Features
Gene ID: 5045
  
Biological name :
  
Synonyms : FURIN / furin, paired basic amino acid cleaving enzyme / FUR|PACE|PCSK3|SPC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201945_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4505579
RefSeq - 577019578
RefSeq - 577019580
RefSeq - NC_000015.10
RefSeq - NP_001276752.1
RefSeq - NP_001276753.1
RefSeq - NP_002560.1
RefSeq - NM_001289823.1
RefSeq - NM_001289824.1
RefSeq - NM_002569.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000140564 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing TAS
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0016485 protein processing IMP
 biological_processGO:0016486 peptide hormone processing IDA
 biological_processGO:0019058 viral life cycle IEP
 biological_processGO:0019082 viral protein processing TAS
 biological_processGO:0022617 extracellular matrix disassembly TAS
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030574 collagen catabolic process TAS
 biological_processGO:0031638 zymogen activation IMP
 biological_processGO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process IDA
 biological_processGO:0032902 nerve growth factor production IDA
 biological_processGO:0032904 negative regulation of nerve growth factor production IDA
 biological_processGO:0032911 negative regulation of transforming growth factor beta1 production IMP
 biological_processGO:0032940 secretion by cell IDA
 biological_processGO:0042176 regulation of protein catabolic process IMP
 biological_processGO:0043043 peptide biosynthetic process IDA
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process IEA
 biological_processGO:0051004 regulation of lipoprotein lipase activity TAS
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis IC
 biological_processGO:0052548 regulation of endopeptidase activity IDA
 biological_processGO:0070268 cornification TAS
 biological_processGO:0090472 dibasic protein processing IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005783 endoplasmic reticulum IGI
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030140 trans-Golgi network transport vesicle IDA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004175 endopeptidase activity TAS
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0042277 peptide binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048406 nerve growth factor binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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