5058


Homo sapiens (NCBI)

Features
Gene ID: 5058
  
Biological name :
  
Synonyms : p21 (RAC1) activated kinase 1 / PAK1 / PAKalpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1565772_at (Human Genome U133 Plus 2.0 Array)   209615_s_at (Human Genome U133 Plus 2.0 Array)   226507_at (Human Genome U133 Plus 2.0 Array)   230100_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 42794769
RefSeq - 1034574010
RefSeq - 1034574012
RefSeq - 1034574014
RefSeq - 1034574016
RefSeq - 1370459539
RefSeq - 1370459542
RefSeq - 1370459544
RefSeq - 1370459547
RefSeq - 1370459549
RefSeq - 1370459551
RefSeq - 1370459553
RefSeq - 1370459555
RefSeq - 190886457
RefSeq - 1034574003
RefSeq - 767968303
RefSeq - 767968305
RefSeq - 767968307
RefSeq - 767968309
RefSeq - 767968311
RefSeq - NC_000011.10
RefSeq - NG_029900.1
RefSeq - NP_001122092.1
RefSeq - NP_002567.3
RefSeq - XP_011543382.1
RefSeq - XP_011543383.1
RefSeq - XP_011543384.1
RefSeq - XP_011543385.1
RefSeq - XP_011543386.1
RefSeq - XP_016873335.1
RefSeq - XP_016873336.1
RefSeq - XP_016873337.1
RefSeq - XP_016873338.1
RefSeq - XP_016873339.1
RefSeq - XP_024304325.1
RefSeq - XP_024304326.1
RefSeq - XP_024304327.1
RefSeq - XP_024304328.1
RefSeq - XP_024304329.1
RefSeq - XP_024304330.1
RefSeq - XP_024304331.1
RefSeq - XP_024304332.1
RefSeq - NM_001128620.1
RefSeq - NM_002576.4
RefSeq - XM_024448563.1
RefSeq - XM_024448564.1
RefSeq - XM_011545080.3
RefSeq - XM_011545081.2
RefSeq - XM_011545082.2
RefSeq - XM_011545083.2
RefSeq - XM_011545084.3
RefSeq - XM_017017846.1
RefSeq - XM_017017847.2
RefSeq - XM_017017848.1
RefSeq - XM_017017849.1
RefSeq - XM_017017850.1
RefSeq - XM_024448557.1
RefSeq - XM_024448558.1
RefSeq - XM_024448559.1
RefSeq - XM_024448560.1
RefSeq - XM_024448561.1
RefSeq - XM_024448562.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000149269 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IDA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010763 positive regulation of fibroblast migration IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030010 establishment of cell polarity IEA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0031116 positive regulation of microtubule polymerization IMP
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0031532 actin cytoskeleton reorganization IMP
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IDA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042060 wound healing IMP
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0043507 positive regulation of JUN kinase activity IMP
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048012 hepatocyte growth factor receptor signaling pathway IMP
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0048812 neuron projection morphogenesis ISS
 biological_processGO:0050770 regulation of axonogenesis IBA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051496 positive regulation of stress fiber assembly IMP
 biological_processGO:0060244 negative regulation of cell proliferation involved in contact inhibition IMP
 biological_processGO:0061052 negative regulation of cell growth involved in cardiac muscle cell development IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IEA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0014704 intercalated disc ISS
 cellular_componentGO:0030018 Z disc ISS
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031941 filamentous actin NAS
 cellular_componentGO:0031965 nuclear membrane ISS
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0071437 invadopodium IDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0048365 Rac GTPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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