50883


Mus musculus (NCBI)

Features
Gene ID: 50883
  
Biological name :
  
Synonyms : checkpoint kinase 2 / Chek2 / CHK2|Cds1|HUCDS1|Rad53
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422747_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 7710088
RefSeq - NC_000071.6
RefSeq - XP_006535130.1
RefSeq - XP_006535131.2
RefSeq - XP_006535132.1
RefSeq - XP_006535133.1
RefSeq - XP_006535134.2
RefSeq - XP_006535135.2
RefSeq - XP_017176462.1
RefSeq - 1039771966
RefSeq - 1039771968
RefSeq - 1039771970
RefSeq - NP_001350237.1
RefSeq - NP_057890.1
RefSeq - 1039771973
RefSeq - 1390005501
RefSeq - 568935897
RefSeq - 568935901
RefSeq - 568935903
RefSeq - XR_001784718.1
RefSeq - NM_001363308.1
RefSeq - NM_016681.4
RefSeq - XM_006535067.3
RefSeq - XM_006535068.3
RefSeq - XM_006535069.2
RefSeq - XM_006535070.2
RefSeq - XM_006535071.3
RefSeq - XM_006535072.3
RefSeq - XM_017320973.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000029521 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint ISO
 biological_processGO:0000086 G2/M transition of mitotic cell cycle ISO
 biological_processGO:0001302 replicative cell aging ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0006975 DNA damage induced protein phosphorylation ISO
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage ISO
 biological_processGO:0010332 response to gamma radiation IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation ISO
 biological_processGO:0042176 regulation of protein catabolic process ISO
 biological_processGO:0042770 signal transduction in response to DNA damage ISO
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0044257 cellular protein catabolic process ISO
 biological_processGO:0044773 mitotic DNA damage checkpoint IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest ISO
 biological_processGO:0071480 cellular response to gamma radiation IMP
 biological_processGO:0072428 signal transduction involved in intra-S DNA damage checkpoint ISO
 biological_processGO:0090307 mitotic spindle assembly ISO
 biological_processGO:2000002 negative regulation of DNA damage checkpoint ISO
 biological_processGO:2000210 positive regulation of anoikis ISO
 cellular_componentGO:0000781 chromosome, telomeric region ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016605 PML body ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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