51176


Homo sapiens (NCBI)

Features
Gene ID: 51176
  
Biological name :
  
Synonyms : LEF1 / LEF-1|TCF10|TCF1ALPHA|TCF7L3 / lymphoid enhancer binding factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210948_s_at (Human Genome U133 Plus 2.0 Array)   221557_s_at (Human Genome U133 Plus 2.0 Array)   221558_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 195222732
RefSeq - 195222734
RefSeq - 260656057
RefSeq - 530377795
RefSeq - 530377797
RefSeq - 530377799
RefSeq - 578809163
RefSeq - 7705917
RefSeq - NC_000004.12
RefSeq - NG_015798.1
RefSeq - NP_001124185.1
RefSeq - NP_001124186.1
RefSeq - NP_001159591.1
RefSeq - NP_057353.1
RefSeq - XP_005263103.1
RefSeq - XP_005263104.1
RefSeq - XP_005263105.1
RefSeq - XP_006714296.1
RefSeq - NM_001130713.2
RefSeq - NM_001130714.2
RefSeq - NM_001166119.1
RefSeq - NM_016269.4
RefSeq - XM_005263046.3
RefSeq - XM_005263047.1
RefSeq - XM_005263048.1
RefSeq - XM_006714233.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000138795 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IBA
 biological_processGO:0001649 osteoblast differentiation IEP
 biological_processGO:0001756 somitogenesis IBA
 biological_processGO:0001837 epithelial to mesenchymal transition ISS
 biological_processGO:0002040 sprouting angiogenesis IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0007223 Wnt signaling pathway, calcium modulating pathway TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0016055 Wnt signaling pathway IDA
 biological_processGO:0016202 regulation of striated muscle tissue development IBA
 biological_processGO:0021542 dentate gyrus development IBA
 biological_processGO:0021861 forebrain radial glial cell differentiation IBA
 biological_processGO:0021873 forebrain neuroblast division IBA
 biological_processGO:0021943 formation of radial glial scaffolds IBA
 biological_processGO:0022407 regulation of cell-cell adhesion IBA
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0030307 positive regulation of cell growth IMP
 biological_processGO:0030326 embryonic limb morphogenesis IBA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0030854 positive regulation of granulocyte differentiation IMP
 biological_processGO:0030879 mammary gland development IBA
 biological_processGO:0032696 negative regulation of interleukin-13 production IDA
 biological_processGO:0032713 negative regulation of interleukin-4 production IDA
 biological_processGO:0032714 negative regulation of interleukin-5 production IDA
 biological_processGO:0033153 T cell receptor V(D)J recombination IEA
 biological_processGO:0042100 B cell proliferation IBA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0043392 negative regulation of DNA binding IDA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043586 tongue development IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IDA
 biological_processGO:0043966 histone H3 acetylation IMP
 biological_processGO:0043967 histone H4 acetylation IMP
 biological_processGO:0045063 T-helper 1 cell differentiation ISS
 biological_processGO:0045843 negative regulation of striated muscle tissue development IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046632 alpha-beta T cell differentiation IBA
 biological_processGO:0048069 eye pigmentation IBA
 biological_processGO:0048341 paraxial mesoderm formation IBA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0060033 anatomical structure regression IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IMP
 biological_processGO:0060325 face morphogenesis IBA
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0060561 apoptotic process involved in morphogenesis IBA
 biological_processGO:0060710 chorio-allantoic fusion IBA
 biological_processGO:0061153 trachea gland development IBA
 biological_processGO:0062009 secondary palate development ISS
 biological_processGO:0071345 cellular response to cytokine stimulus IMP
 biological_processGO:0071353 cellular response to interleukin-4 IDA
 biological_processGO:0071864 positive regulation of cell proliferation in bone marrow IMP
 biological_processGO:0071866 negative regulation of apoptotic process in bone marrow IMP
 biological_processGO:0071895 odontoblast differentiation IBA
 biological_processGO:0071899 negative regulation of estrogen receptor binding IDA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IEA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:1990907 beta-catenin-TCF complex IPI
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding TAS
 molecular_functionGO:0008301 DNA binding, bending ISS
 molecular_functionGO:0030284 estrogen receptor activity IDA
 molecular_functionGO:0030331 estrogen receptor binding IDA
 molecular_functionGO:0035326 enhancer binding IDA
 molecular_functionGO:0042393 histone binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IMP
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0045295 gamma-catenin binding IPI
 molecular_functionGO:0070016 armadillo repeat domain binding IPI
 molecular_functionGO:0070742 C2H2 zinc finger domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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