5142


Homo sapiens (NCBI)
regulationbindingcellularresponsechannelneutrophilcampreceptorsignalingpathwayproductioncellcardiacmusclevoltage-gatedcalciumactivitygamma-tubulincomplexionhomeostasiscatabolicprocessg-proteincoupledchemotaxisinterferon-gammainterleukin-drugt

Features
Gene ID: 5142
  
Biological name :
  
Synonyms : DPDE4|PDEIVB / PDE4B / phosphodiesterase 4B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203708_at (Human Genome U133 Plus 2.0 Array)   211302_s_at (Human Genome U133 Plus 2.0 Array)   215671_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034559079
RefSeq - 32171241
RefSeq - 530362749
RefSeq - 530362751
RefSeq - 578799224
RefSeq - 661903028
RefSeq - 661903030
RefSeq - 661903032
RefSeq - 82799482
RefSeq - 82799484
RefSeq - 82799486
RefSeq - NC_000001.11
RefSeq - NG_029038.1
RefSeq - NP_001032416.1
RefSeq - NP_001032417.1
RefSeq - NP_001032418.1
RefSeq - NP_001284369.1
RefSeq - NP_001284370.1
RefSeq - NP_001284371.1
RefSeq - NP_002591.2
RefSeq - XP_005270981.1
RefSeq - XP_005270982.1
RefSeq - XP_006710743.1
RefSeq - XP_016856934.1
RefSeq - NM_001037339.2
RefSeq - NM_001037340.2
RefSeq - NM_001037341.1
RefSeq - NM_001297440.1
RefSeq - NM_001297441.1
RefSeq - NM_001297442.1
RefSeq - NM_002600.3
RefSeq - XM_005270925.2
RefSeq - XM_006710680.3
RefSeq - XM_017001445.1
RefSeq - XM_005270924.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000184588 to get all the annotations available for this gene.


Gene Ontology (GO)
regulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregulation of biological qualitynitrogen compound metabolic processbiosynthetic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicallocalization of cellmovement of cell or subcellular componentcytokine productionimmune responseresponse to biotic stimulusresponse to endogenous stimulussystem processactin filament-based processestablishment of localizationregulation of molecular functionregularegulation of biological qualitynitrognitrogen compound metabolic processbiosynbiosynthetic processcatabocatabolic processcellulcellular metabolic processprimarprimary metabolic processsmall small molecule metabolic processorganiorganic substance metabolic processcell ccell communicationcellulcellular response to stimulusresponresponse to external stimulusresponresponse to chemicallocalilocalization of cellmovememovement of cell or subcellular componentcytokicytokine productionimmuneimmune responseresponresponse to biotic stimulusresponresponse to endogenous stimulussystemsystem processactin actin filament-based processestablestablishment of localizationregularegulation of molecular function
hydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityhydrolase activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingprotein bindingprotein binding
cellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellprotein-containing complexorganellemembranesynapsesupramolecular complexcellcellprotein-containing compprotein-containing complexorganelleorganellemembranemembranesynapsesynapsesupramolecular complexsupramolecular complex
TypeGO IDTermEv.Code
 biological_processGO:0001780 neutrophil homeostasis ISS
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0030593 neutrophil chemotaxis ISS
 biological_processGO:0032729 positive regulation of interferon-gamma production IMP
 biological_processGO:0032743 positive regulation of interleukin-2 production IMP
 biological_processGO:0035690 cellular response to drug ISS
 biological_processGO:0050852 T cell receptor signaling pathway IMP
 biological_processGO:0050900 leukocyte migration ISS
 biological_processGO:0071222 cellular response to lipopolysaccharide ISS
 biological_processGO:0071872 cellular response to epinephrine stimulus ISS
 biological_processGO:0086004 regulation of cardiac muscle cell contraction ISS
 biological_processGO:1901841 regulation of high voltage-gated calcium channel activity ISS
 biological_processGO:1901898 negative regulation of relaxation of cardiac muscle ISS
 cellular_componentGO:0000930 gamma-tubulin complex IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005891 voltage-gated calcium channel complex ISS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030018 Z disc ISS
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity TAS
 molecular_functionGO:0030552 cAMP binding IGI
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0044325 ion channel binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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