5144


Homo sapiens (NCBI)

Features
Gene ID: 5144
  
Biological name :
  
Synonyms : ACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1 / PDE4D / phosphodiesterase 4D
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554717_a_at (Human Genome U133 Plus 2.0 Array)   204491_at (Human Genome U133 Plus 2.0 Array)   210836_x_at (Human Genome U133 Plus 2.0 Array)   210837_s_at (Human Genome U133 Plus 2.0 Array)   211840_s_at (Human Genome U133 Plus 2.0 Array)   228962_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 308387382
RefSeq - 1034645219
RefSeq - 1034645221
RefSeq - 1034645230
RefSeq - 1154067826
RefSeq - 1154067828
RefSeq - 1154067830
RefSeq - 1370496189
RefSeq - 1370496209
RefSeq - 1370496237
RefSeq - 157277988
RefSeq - 259906420
RefSeq - 308387374
RefSeq - 308387376
RefSeq - 308387378
RefSeq - 308387380
RefSeq - 1034645216
RefSeq - 308387384
RefSeq - 32306513
RefSeq - 767936081
RefSeq - 767936083
RefSeq - 767936085
RefSeq - 767936089
RefSeq - NC_000005.10
RefSeq - NG_027957.1
RefSeq - NP_001098101.1
RefSeq - NP_001159371.1
RefSeq - NP_001184147.1
RefSeq - NP_001184148.1
RefSeq - NP_001184149.1
RefSeq - NP_001184150.1
RefSeq - NP_001184151.1
RefSeq - NP_001184152.1
RefSeq - NP_001336170.1
RefSeq - NP_001336171.1
RefSeq - NP_001336172.1
RefSeq - NP_006194.2
RefSeq - XP_011541771.1
RefSeq - XP_011541772.1
RefSeq - XP_011541773.1
RefSeq - XP_011541775.1
RefSeq - XP_016865054.1
RefSeq - XP_016865055.1
RefSeq - XP_016865056.1
RefSeq - XP_016865059.1
RefSeq - XP_024301878.1
RefSeq - XP_024301879.1
RefSeq - XP_024301880.1
RefSeq - NM_001104631.1
RefSeq - NM_001165899.1
RefSeq - NM_001197218.1
RefSeq - NM_001197219.1
RefSeq - NM_001197220.1
RefSeq - NM_001197221.1
RefSeq - NM_001197222.1
RefSeq - NM_001197223.1
RefSeq - NM_001349241.1
RefSeq - NM_001349242.1
RefSeq - NM_001349243.1
RefSeq - NM_006203.4
RefSeq - XM_024446112.1
RefSeq - XM_011543469.1
RefSeq - XM_011543470.2
RefSeq - XM_011543471.2
RefSeq - XM_011543473.1
RefSeq - XM_017009565.1
RefSeq - XM_017009566.1
RefSeq - XM_017009567.1
RefSeq - XM_017009570.2
RefSeq - XM_024446110.1
RefSeq - XM_024446111.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000113448 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002027 regulation of heart rate ISS
 biological_processGO:0006198 cAMP catabolic process IMP
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0010469 regulation of signaling receptor activity ISS
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISS
 biological_processGO:0019933 cAMP-mediated signaling NAS
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IMP
 biological_processGO:0032743 positive regulation of interleukin-2 production IMP
 biological_processGO:0032754 positive regulation of interleukin-5 production IMP
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation ISS
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0045822 negative regulation of heart contraction ISS
 biological_processGO:0050852 T cell receptor signaling pathway IMP
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity ISS
 biological_processGO:0061028 establishment of endothelial barrier ISS
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071872 cellular response to epinephrine stimulus IEA
 biological_processGO:0071875 adrenergic receptor signaling pathway ISS
 biological_processGO:0086004 regulation of cardiac muscle cell contraction ISS
 biological_processGO:0086024 adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate IC
 biological_processGO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction IC
 biological_processGO:1901898 negative regulation of relaxation of cardiac muscle ISS
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005891 voltage-gated calcium channel complex ISS
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0034704 calcium channel complex IDA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity NAS
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IPI
 molecular_functionGO:0019899 enzyme binding ISS
 molecular_functionGO:0030552 cAMP binding IDA
 molecular_functionGO:0031698 beta-2 adrenergic receptor binding ISS
 molecular_functionGO:0044325 ion channel binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding IPI
 molecular_functionGO:0097110 scaffold protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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