5154


Homo sapiens (NCBI)

Features
Gene ID: 5154
  
Biological name :
  
Synonyms : PDGFA / PDGF-A|PDGF1 / platelet derived growth factor subunit A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205463_s_at (Human Genome U133 Plus 2.0 Array)   216867_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016867778.1
RefSeq - 15208656
RefSeq - 767945536
RefSeq - 767945538
RefSeq - 767945540
RefSeq - 767945542
RefSeq - 767945544
RefSeq - 77695917
RefSeq - NC_000007.14
RefSeq - NG_029727.1
RefSeq - NP_002598.4
RefSeq - NP_148983.1
RefSeq - XP_011513717.1
RefSeq - XP_011513718.1
RefSeq - XP_011513719.1
RefSeq - XP_011513720.1
RefSeq - XP_011513721.1
RefSeq - 1034655854
RefSeq - NM_002607.5
RefSeq - NM_033023.4
RefSeq - XM_011515419.3
RefSeq - XM_017012289.1
RefSeq - XM_011515415.1
RefSeq - XM_011515416.1
RefSeq - XM_011515417.1
RefSeq - XM_011515418.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000197461 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001525 angiogenesis ISS
 biological_processGO:0001775 cell activation TAS
 biological_processGO:0001942 hair follicle development ISS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISS
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0009611 response to wounding IDA
 biological_processGO:0009887 animal organ morphogenesis ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010512 negative regulation of phosphatidylinositol biosynthetic process IDA
 biological_processGO:0010544 negative regulation of platelet activation IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0014910 regulation of smooth muscle cell migration IDA
 biological_processGO:0030031 cell projection assembly ISS
 biological_processGO:0030036 actin cytoskeleton organization ISS
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0032956 regulation of actin cytoskeleton organization TAS
 biological_processGO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway IDA
 biological_processGO:0042060 wound healing TAS
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043588 skin development ISS
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IDA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0048286 lung alveolus development ISS
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation ISS
 biological_processGO:0050919 negative chemotaxis IDA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0072124 regulation of glomerular mesangial cell proliferation IDA
 biological_processGO:1990401 embryonic lung development ISS
 biological_processGO:2000278 regulation of DNA biosynthetic process IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005902 microvillus ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0048407 platelet-derived growth factor binding IPI
 molecular_functionGO:0070851 growth factor receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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