5244


Homo sapiens (NCBI)

Features
Gene ID: 5244
  
Biological name :
  
Synonyms : ABC21|GBD1|ICP3|MDR2|MDR2/3|MDR3|PFIC-3|PGY3 / ABCB4 / ATP binding cassette subfamily B member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1570505_at (Human Genome U133 Plus 2.0 Array)   207819_s_at (Human Genome U133 Plus 2.0 Array)   209994_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034655960
RefSeq - 1034655962
RefSeq - 1370510362
RefSeq - 1370510364
RefSeq - 1370510366
RefSeq - 1370510368
RefSeq - 1370510370
RefSeq - 1370510372
RefSeq - 4505771
RefSeq - 9961250
RefSeq - 9961252
RefSeq - NC_000007.14
RefSeq - NG_007118.1
RefSeq - NP_000434.1
RefSeq - NP_061337.1
RefSeq - NP_061338.1
RefSeq - XP_011514610.3
RefSeq - XP_011514611.3
RefSeq - XP_011514612.3
RefSeq - XP_011514613.3
RefSeq - XP_011514614.3
RefSeq - XP_011514615.2
RefSeq - XP_011514617.2
RefSeq - XP_016867812.1
RefSeq - XM_011516313.3
RefSeq - XM_011516315.3
RefSeq - NM_000443.3
RefSeq - NM_018849.2
RefSeq - NM_018850.2
RefSeq - XM_017012323.2
RefSeq - XR_001744809.2
RefSeq - XR_001744810.2
RefSeq - XM_011516308.3
RefSeq - XM_011516309.3
RefSeq - XM_011516310.3
RefSeq - XM_011516311.3
RefSeq - XM_011516312.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000005471 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0009914 hormone transport IEA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0032376 positive regulation of cholesterol transport IMP
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032782 bile acid secretion ISS
 biological_processGO:0033189 response to vitamin A IEA
 biological_processGO:0033231 carbohydrate export IEA
 biological_processGO:0033280 response to vitamin D IEA
 biological_processGO:0033762 response to glucagon IEA
 biological_processGO:0035633 maintenance of permeability of blood-brain barrier IEA
 biological_processGO:0036146 cellular response to mycotoxin IEA
 biological_processGO:0042493 response to drug TAS
 biological_processGO:0042908 xenobiotic transport IEA
 biological_processGO:0043215 daunorubicin transport IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0045332 phospholipid translocation IMP
 biological_processGO:0046618 drug export IEA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0050892 intestinal absorption IEA
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0055088 lipid homeostasis IDA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0060856 establishment of blood-brain barrier IEA
 biological_processGO:0061092 positive regulation of phospholipid translocation IDA
 biological_processGO:0071217 cellular response to external biotic stimulus IEA
 biological_processGO:0071236 cellular response to antibiotic IEA
 biological_processGO:0071312 cellular response to alkaloid IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0071475 cellular hyperosmotic salinity response IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0097068 response to thyroxine IEA
 biological_processGO:0099040 ceramide translocation IDA
 biological_processGO:1901557 response to fenofibrate ISS
 biological_processGO:1903413 cellular response to bile acid IDA
 biological_processGO:1903416 response to glycoside IEA
 biological_processGO:1904478 regulation of intestinal absorption IEA
 biological_processGO:1905231 cellular response to borneol IEA
 biological_processGO:1905232 cellular response to L-glutamate IEA
 biological_processGO:1905233 response to codeine IEA
 biological_processGO:1905235 response to quercetin IEA
 biological_processGO:1905237 response to cyclosporin A IEA
 biological_processGO:1990962 drug transport across blood-brain barrier IEA
 biological_processGO:1990963 establishment of blood-retinal barrier IEA
 biological_processGO:2001025 positive regulation of response to drug IEA
 biological_processGO:2001140 positive regulation of phospholipid transport IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0031526 brush border membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046581 intercellular canaliculus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005548 phospholipid transporter activity TAS
 molecular_functionGO:0008525 phosphatidylcholine transporter activity IMP
 molecular_functionGO:0008559 xenobiotic transmembrane transporting ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IMP
 molecular_functionGO:0090554 phosphatidylcholine-translocating ATPase activity IMP
 molecular_functionGO:0099038 ceramide-translocating ATPase activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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