5294


Homo sapiens (NCBI)

Features
Gene ID: 5294
  
Biological name :
  
Synonyms : phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma / PI3CG|PI3K|PI3Kgamma|PIK3|p110gamma|p120-PI3K / PIK3CG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206369_s_at (Human Genome U133 Plus 2.0 Array)   206370_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034655976
RefSeq - 21237725
RefSeq - 530386106
RefSeq - 539846630
RefSeq - 539846764
RefSeq - 767948059
RefSeq - 767948061
RefSeq - NC_000007.14
RefSeq - NG_050579.1
RefSeq - NP_001269355.1
RefSeq - NP_001269356.1
RefSeq - NP_002640.2
RefSeq - XP_005250500.1
RefSeq - XP_011514618.1
RefSeq - XP_011514619.1
RefSeq - XP_016867817.1
RefSeq - NM_001282426.1
RefSeq - NM_001282427.1
RefSeq - NM_002649.3
RefSeq - XM_011516316.1
RefSeq - XM_011516317.1
RefSeq - XM_017012328.1
RefSeq - XM_005250443.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000105851 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001816 cytokine production TAS
 biological_processGO:0002250 adaptive immune response TAS
 biological_processGO:0002407 dendritic cell chemotaxis TAS
 biological_processGO:0002675 positive regulation of acute inflammatory response IEA
 biological_processGO:0002679 respiratory burst involved in defense response TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0010818 T cell chemotaxis TAS
 biological_processGO:0010897 negative regulation of triglyceride catabolic process IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling TAS
 biological_processGO:0016310 phosphorylation IDA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030593 neutrophil chemotaxis TAS
 biological_processGO:0032252 secretory granule localization IEA
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin TAS
 biological_processGO:0035747 natural killer cell chemotaxis TAS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042098 T cell proliferation TAS
 biological_processGO:0042110 T cell activation TAS
 biological_processGO:0043303 mast cell degranulation TAS
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IBA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0055118 negative regulation of cardiac muscle contraction TAS
 biological_processGO:0070527 platelet aggregation TAS
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0072672 neutrophil extravasation TAS
 biological_processGO:0097284 hepatocyte apoptotic process IEA
 biological_processGO:1903169 regulation of calcium ion transmembrane transport IEA
 biological_processGO:2000270 negative regulation of fibroblast apoptotic process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex IBA
 cellular_componentGO:0005944 phosphatidylinositol 3-kinase complex, class IB IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0042629 mast cell granule IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IDA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity IBA
 molecular_functionGO:0035004 phosphatidylinositol 3-kinase activity TAS
 molecular_functionGO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0052742 phosphatidylinositol kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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