5341


Homo sapiens (NCBI)

Features
Gene ID: 5341
  
Biological name :
  
Synonyms : P47 / pleckstrin / PLEK
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203470_s_at (Human Genome U133 Plus 2.0 Array)   203471_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 156616273
RefSeq - NC_000002.12
RefSeq - NP_002655.2
RefSeq - NM_002664.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000115956 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEP
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis ISS
 biological_processGO:0007229 integrin-mediated signaling pathway IDA
 biological_processGO:0010572 positive regulation of platelet activation ISS
 biological_processGO:0010920 negative regulation of inositol phosphate biosynthetic process IDA
 biological_processGO:0010925 positive regulation of inositol-polyphosphate 5-phosphatase activity IDA
 biological_processGO:0030030 cell projection organization IDA
 biological_processGO:0030836 positive regulation of actin filament depolymerization IDA
 biological_processGO:0030845 phospholipase C-inhibiting G-protein coupled receptor signaling pathway IDA
 biological_processGO:0030866 cortical actin cytoskeleton organization IDA
 biological_processGO:0031529 ruffle organization IDA
 biological_processGO:0031532 actin cytoskeleton reorganization IDA
 biological_processGO:0032233 positive regulation of actin filament bundle assembly IDA
 biological_processGO:0033625 positive regulation of integrin activation ISS
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0046488 phosphatidylinositol metabolic process IDA
 biological_processGO:0050849 negative regulation of calcium-mediated signaling NAS
 biological_processGO:0060305 regulation of cell diameter IDA
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IDA
 biological_processGO:0070527 platelet aggregation ISS
 biological_processGO:0070528 protein kinase C signaling ISS
 biological_processGO:0070560 protein secretion by platelet ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032587 ruffle membrane IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0005080 protein kinase C binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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