54106


Homo sapiens (NCBI)

Features
Gene ID: 54106
  
Biological name :
  
Synonyms : CD289 / TLR9 / toll like receptor 9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 223903_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 8394456
RefSeq - NC_000003.12
RefSeq - NG_033933.1
RefSeq - NP_059138.1
RefSeq - NM_017442.3
RefSeq - NM_138688.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000239732 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002237 response to molecule of bacterial origin TAS
 biological_processGO:0002639 positive regulation of immunoglobulin production IDA
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IBA
 biological_processGO:0007252 I-kappaB phosphorylation IDA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0030277 maintenance of gastrointestinal epithelium ISS
 biological_processGO:0030890 positive regulation of B cell proliferation IDA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032640 tumor necrosis factor production IDA
 biological_processGO:0032715 negative regulation of interleukin-6 production ISS
 biological_processGO:0032717 negative regulation of interleukin-8 production IDA
 biological_processGO:0032722 positive regulation of chemokine production IDA
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production IDA
 biological_processGO:0032728 positive regulation of interferon-beta production ISS
 biological_processGO:0032733 positive regulation of interleukin-10 production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032741 positive regulation of interleukin-18 production ISS
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISS
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IDA
 biological_processGO:0034123 positive regulation of toll-like receptor signaling pathway IDA
 biological_processGO:0034162 toll-like receptor 9 signaling pathway TAS
 biological_processGO:0034163 regulation of toll-like receptor 9 signaling pathway IDA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042742 defense response to bacterium NAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043507 positive regulation of JUN kinase activity IDA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process IDA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045356 positive regulation of interferon-alpha biosynthetic process IDA
 biological_processGO:0045359 positive regulation of interferon-beta biosynthetic process IDA
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process IBA
 biological_processGO:0045577 regulation of B cell differentiation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046330 positive regulation of JNK cascade IC
 biological_processGO:0050707 regulation of cytokine secretion IEA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0050871 positive regulation of B cell activation IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process ISS
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IDA
 biological_processGO:1901895 negative regulation of calcium-transporting ATPase activity IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0032009 early phagosome ISS
 cellular_componentGO:0036020 endolysosome membrane TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005149 interleukin-1 receptor binding IPI
 molecular_functionGO:0008329 signaling pattern recognition receptor activity IBA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0035197 siRNA binding IMP
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0045322 unmethylated CpG binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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