54541


Homo sapiens (NCBI)
regulationresponseneuronsignalingphosphorylationpathwayprocessintracellular-hypoxiamigrationbraindevelopmentcellproliferationpeptidyl-threoninedifferentiationtorprotein-containingcomplexdisassemblypeptidyl-serineintrinsicapoptoticdnadamagepclassmediatorglycolytic

Features
Gene ID: 54541
  
Biological name :
  
Synonyms : DDIT4 / Dig2|REDD-1|REDD1 / DNA damage inducible transcript 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202887_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 9506687
RefSeq - NC_000010.11
RefSeq - NP_061931.1
RefSeq - NM_019058.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000168209 to get all the annotations available for this gene.


Gene Ontology (GO)
response to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponse to stressresponse to abiotic stimuluslocalization of cellmovement of cell or subcellular componentanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular component organizationcell deathbiosynthetic processcatabolic processsmall molecule metabolic processresponse to chemicalresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to endogenous stimulusresponresponse to stressresponresponse to abiotic stimuluslocalilocalization of cellmovememovement of cell or subcellular componentanatomanatomical structure developmentcellulcellular developmental processnitrognitrogen compound metabolic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processcell ccell communicationcellulcellular response to stimuluscellulcellular component organizationcell dcell deathbiosynbiosynthetic processcatabocatabolic processsmall small molecule metabolic processresponresponse to chemicalresponresponse to external stimulusresponresponse to biotic stimulusimmuneimmune effector processresponresponse to endogenous stimulus
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation ISS
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0032007 negative regulation of TOR signaling IMP
 biological_processGO:0032984 protein-containing complex disassembly IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation ISS
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISS
 biological_processGO:0045820 negative regulation of glycolytic process IEA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway ISS
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902532 negative regulation of intracellular signal transduction ISS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr