ENSG00000168209


Homo sapiens

Features
Gene ID: ENSG00000168209
  
Biological name :DDIT4
  
Synonyms : DDIT4 / DNA damage inducible transcript 4 / Q9NX09
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.1
Gene start: 72273920
Gene end: 72276036
  
Corresponding Affymetrix probe sets: 202887_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307305
NCBI entrez gene - 54541     See in Manteia.
OMIM - 607729
RefSeq - NM_019058
RefSeq Peptide - NP_061931
swissprot - A0A024QZQ6
swissprot - Q9NX09
Ensembl - ENSG00000168209
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddit4ENSDARG00000037618Danio rerio
 DDIT4ENSGALG00000041459Gallus gallus
 Ddit4ENSMUSG00000020108Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDIT4L / Q96D03 / DNA damage inducible transcript 4 likeENSG0000014535827


Protein motifs (from Interpro)
Interpro ID Name
 IPR012918  RTP801-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation ISS
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0032007 negative regulation of TOR signaling IMP
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation ISS
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISS
 biological_processGO:0045820 negative regulation of glycolytic process IEA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway ISS
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902532 negative regulation of intracellular signal transduction ISS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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