54626


Homo sapiens (NCBI)
bindingdnatranscriptionrnapolymeraseiiactivityregulationproximalpromoterfactorsomitogenesisdna-templatednotchsignalingpathwaycelldifferentiationneurogenesisnucleusregulatoryregiontranscriptionalrepressorcorepressorproteindimerizationdouble-stranded

Features
Gene ID: 54626
  
Biological name :
  
Synonyms : bHLHb40 / HES2 / hes family bHLH transcription factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 214521_at (Human Genome U133 Plus 2.0 Array)   216674_at (Human Genome U133 Plus 2.0 Array)   231928_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 63055047
RefSeq - NC_000001.11
RefSeq - NP_061962.2
RefSeq - NM_019089.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000069812 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluscellular developmental processnitrogen compounitrogen compound metabolic processbiosynthetic prbiosynthetic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processanatomical struanatomical structure developmentcell communicatcell communicationcellular responcellular response to stimuluscellular develocellular developmental process
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription coregulator activityprotein bindingorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound bindingDNA-binding transcription faDNA-binding transcription factor activitytranscription coregulator actranscription coregulator activityprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001756 somitogenesis IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0050767 regulation of neurogenesis IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:1990837 sequence-specific double-stranded DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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