5465


Homo sapiens (NCBI)

Features
Gene ID: 5465
  
Biological name :
  
Synonyms : NR1C1|PPAR|PPARalpha|hPPAR / peroxisome proliferator activated receptor alpha / PPARA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1558631_at (Human Genome U133 Plus 2.0 Array)   1560981_a_at (Human Genome U133 Plus 2.0 Array)   206870_at (Human Genome U133 Plus 2.0 Array)   210771_at (Human Genome U133 Plus 2.0 Array)   223437_at (Human Genome U133 Plus 2.0 Array)   223438_s_at (Human Genome U133 Plus 2.0 Array)   226978_at (Human Genome U133 Plus 2.0 Array)   237142_at (Human Genome U133 Plus 2.0 Array)   244689_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 768025172
RefSeq - 1370482364
RefSeq - 1370482366
RefSeq - 1385123318
RefSeq - 1385123351
RefSeq - 50348666
RefSeq - 530420193
RefSeq - 530420195
RefSeq - 578837280
RefSeq - 578837282
RefSeq - 7549811
RefSeq - 768025152
RefSeq - 768025160
RefSeq - 768025164
RefSeq - 1034629122
RefSeq - 768025181
RefSeq - 768025185
RefSeq - 768025190
RefSeq - NC_000022.11
RefSeq - NG_012204.1
RefSeq - NP_001001928.1
RefSeq - NP_001349801.1
RefSeq - NP_001349802.1
RefSeq - NP_005027.2
RefSeq - XP_005261712.1
RefSeq - XP_005261713.1
RefSeq - XP_006724332.1
RefSeq - XP_006724333.1
RefSeq - XP_011528541.1
RefSeq - XP_011528542.1
RefSeq - XP_011528543.1
RefSeq - XP_011528544.1
RefSeq - XP_011528545.1
RefSeq - XP_011528546.1
RefSeq - XP_011528547.1
RefSeq - XP_016884328.1
RefSeq - XP_024308020.1
RefSeq - XP_024308021.1
RefSeq - XM_011530242.2
RefSeq - XM_011530243.2
RefSeq - XM_011530244.2
RefSeq - XM_011530245.2
RefSeq - XM_017028839.1
RefSeq - XM_024452252.1
RefSeq - NM_001001928.3
RefSeq - NM_001001929.2
RefSeq - NM_001001930.2
RefSeq - NM_001362872.1
RefSeq - NM_001362873.1
RefSeq - NM_005036.5
RefSeq - NM_032644.3
RefSeq - XM_024452253.1
RefSeq - XR_937869.2
RefSeq - XR_937870.2
RefSeq - XR_001755253.1
RefSeq - XM_005261655.3
RefSeq - XM_005261656.3
RefSeq - XM_006724269.3
RefSeq - XM_006724270.3
RefSeq - XM_011530239.2
RefSeq - XM_011530240.2
RefSeq - XM_011530241.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000186951 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008544 epidermis development IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IDA
 biological_processGO:0010871 negative regulation of receptor biosynthetic process IDA
 biological_processGO:0010887 negative regulation of cholesterol storage IDA
 biological_processGO:0010891 negative regulation of sequestering of triglyceride IDA
 biological_processGO:0015908 fatty acid transport TAS
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0031667 response to nutrient levels IBA
 biological_processGO:0032000 positive regulation of fatty acid beta-oxidation TAS
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032099 negative regulation of appetite ISS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032922 circadian regulation of gene expression ISS
 biological_processGO:0033993 response to lipid IBA
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042157 lipoprotein metabolic process IEA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045722 positive regulation of gluconeogenesis IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045820 negative regulation of glycolytic process IC
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045923 positive regulation of fatty acid metabolic process IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046321 positive regulation of fatty acid oxidation ISS
 biological_processGO:0050728 negative regulation of inflammatory response IDA
 biological_processGO:0070166 enamel mineralization IEA
 biological_processGO:0071396 cellular response to lipid IBA
 biological_processGO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter IDA
 biological_processGO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter IDA
 biological_processGO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter IDA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:1903038 negative regulation of leukocyte cell-cell adhesion IDA
 biological_processGO:2000678 negative regulation of transcription regulatory region DNA binding IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IPI
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001223 transcription coactivator binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0003707 steroid hormone receptor activity IDA
 molecular_functionGO:0004879 nuclear receptor activity IDA
 molecular_functionGO:0005504 fatty acid binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IDA
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IBA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051525 NFAT protein binding IEA
 molecular_functionGO:0097371 MDM2/MDM4 family protein binding IEA
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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