5494


Homo sapiens (NCBI)

Features
Gene ID: 5494
  
Biological name :
  
Synonyms : PP2C-ALPHA|PP2CA|PP2Calpha / PPM1A / protein phosphatase, Mg2+/Mn2+ dependent 1A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203966_s_at (Human Genome U133 Plus 2.0 Array)   210407_at (Human Genome U133 Plus 2.0 Array)   227728_at (Human Genome U133 Plus 2.0 Array)   229027_at (Human Genome U133 Plus 2.0 Array)   231370_at (Human Genome U133 Plus 2.0 Array)   235344_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767980822
RefSeq - 1034587342
RefSeq - 1034587344
RefSeq - 1034587346
RefSeq - 1034587351
RefSeq - 1034587353
RefSeq - 1034587355
RefSeq - 1034587358
RefSeq - 1370465204
RefSeq - 193211600
RefSeq - 29557855
RefSeq - 530404023
RefSeq - 530404027
RefSeq - 767980810
RefSeq - 767980818
RefSeq - 767980820
RefSeq - 10337595
RefSeq - 767980824
RefSeq - 767980826
RefSeq - 767980828
RefSeq - 767980830
RefSeq - 767980832
RefSeq - NC_000014.9
RefSeq - NG_029698.1
RefSeq - NP_066283.1
RefSeq - NP_808820.1
RefSeq - NP_808821.2
RefSeq - XP_005267836.1
RefSeq - XP_005267838.1
RefSeq - XP_011535174.1
RefSeq - XP_011535178.1
RefSeq - XP_011535179.1
RefSeq - XP_011535180.1
RefSeq - XP_011535181.1
RefSeq - XP_011535182.1
RefSeq - XP_011535183.1
RefSeq - XP_011535184.1
RefSeq - XP_011535185.1
RefSeq - XP_016876870.1
RefSeq - XP_016876871.1
RefSeq - XP_016876872.1
RefSeq - XP_016876873.1
RefSeq - XP_016876874.1
RefSeq - XP_016876875.1
RefSeq - XP_016876876.1
RefSeq - XP_024305405.1
RefSeq - NM_021003.4
RefSeq - NM_177951.2
RefSeq - NM_177952.2
RefSeq - XM_017021386.1
RefSeq - XM_017021387.1
RefSeq - XM_024449637.1
RefSeq - XM_005267779.1
RefSeq - XM_005267781.1
RefSeq - XM_011536872.1
RefSeq - XM_011536876.1
RefSeq - XM_011536877.1
RefSeq - XM_011536878.1
RefSeq - XM_011536879.3
RefSeq - XM_011536880.3
RefSeq - XM_011536881.3
RefSeq - XM_011536882.2
RefSeq - XM_011536883.1
RefSeq - XM_017021381.1
RefSeq - XM_017021382.1
RefSeq - XM_017021383.1
RefSeq - XM_017021384.1
RefSeq - XM_017021385.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000100614 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006470 protein dephosphorylation IMP
 biological_processGO:0006499 N-terminal protein myristoylation ISS
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0010991 negative regulation of SMAD protein complex assembly IDA
 biological_processGO:0016055 Wnt signaling pathway IDA
 biological_processGO:0016311 dephosphorylation IDA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IDA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling HMP
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046827 positive regulation of protein export from nucleus IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane ISS
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0033192 calmodulin-dependent protein phosphatase activity IDA
 molecular_functionGO:0070412 R-SMAD binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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