55294


Homo sapiens (NCBI)

Features
Gene ID: 55294
  
Biological name :
  
Synonyms : AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4 / F-box and WD repeat domain containing 7 / FBXW7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 218751_s_at (Human Genome U133 Plus 2.0 Array)   222729_at (Human Genome U133 Plus 2.0 Array)   229419_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767932252
RefSeq - 1370487185
RefSeq - 1370487187
RefSeq - 1370487189
RefSeq - 1370487191
RefSeq - 1370487196
RefSeq - 1370487200
RefSeq - 16117779
RefSeq - 16117781
RefSeq - 379991109
RefSeq - 61743926
RefSeq - 767932250
RefSeq - 1168720158
RefSeq - 767932254
RefSeq - 767932256
RefSeq - 767932258
RefSeq - NC_000004.12
RefSeq - NG_029466.2
RefSeq - NP_001013433.1
RefSeq - NP_001243998.1
RefSeq - NP_001336727.1
RefSeq - NP_060785.2
RefSeq - NP_361014.1
RefSeq - XP_011530386.1
RefSeq - XP_011530387.1
RefSeq - XP_011530388.1
RefSeq - XP_011530389.1
RefSeq - XP_011530390.1
RefSeq - XP_024309889.1
RefSeq - XP_024309890.1
RefSeq - XP_024309891.1
RefSeq - XP_024309892.1
RefSeq - XP_024309893.1
RefSeq - XP_024309894.1
RefSeq - NM_001013415.2
RefSeq - NM_001257069.1
RefSeq - NM_001349798.2
RefSeq - NM_018315.5
RefSeq - NM_033632.3
RefSeq - XM_024454122.1
RefSeq - XM_024454123.1
RefSeq - XM_024454124.1
RefSeq - XM_024454125.1
RefSeq - XM_024454126.1
RefSeq - XM_011532084.2
RefSeq - XM_011532085.2
RefSeq - XM_011532086.2
RefSeq - XM_011532087.2
RefSeq - XM_011532088.2
RefSeq - XM_024454121.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000109670 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0001944 vasculature development TAS
 biological_processGO:0007062 sister chromatid cohesion IMP
 biological_processGO:0010868 negative regulation of triglyceride biosynthetic process ISS
 biological_processGO:0010883 regulation of lipid storage ISS
 biological_processGO:0010992 ubiquitin recycling IBA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IDA
 biological_processGO:0032876 negative regulation of DNA endoreduplication IMP
 biological_processGO:0032880 regulation of protein localization ISS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity IDA
 biological_processGO:0045746 negative regulation of Notch signaling pathway ISS
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IDA
 biological_processGO:0055088 lipid homeostasis ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IDA
 biological_processGO:1902806 regulation of cell cycle G1/S phase transition TAS
 biological_processGO:1903146 regulation of autophagy of mitochondrion IMP
 biological_processGO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IDA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IDA
 biological_processGO:2000346 negative regulation of hepatocyte proliferation ISS
 biological_processGO:2000639 negative regulation of SREBP signaling pathway ISS
 biological_processGO:2001205 negative regulation of osteoclast development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 cellular_componentGO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex IPI
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0030674 protein binding, bridging IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043130 ubiquitin binding IBA
 molecular_functionGO:0050816 phosphothreonine residue binding IDA
 molecular_functionGO:0097027 ubiquitin-protein transferase activator activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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