55655


Homo sapiens (NCBI)
regulationbindingapoptoticprocessresponseactivityinflammatorynf-kappabtranscriptionfactorcysteine-typeendopeptidaseinvolvedinnateimmuneinterleukin-betasecretionnuclearchromosometelomericregioncytoplasmgolgiapparatuscytosolintracellularmembrane-boundedorganelleprotein

Features
Gene ID: 55655
  
Biological name :
  
Synonyms : CLR19.9|NALP2|NBS1|PAN1|PYPAF2 / NLR family pyrin domain containing 2 / NLRP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 221690_s_at (Human Genome U133 Plus 2.0 Array)   237489_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NW_003571061.2
RefSeq - 291463275
RefSeq - 291463278
RefSeq - 291463280
RefSeq - 8923473
RefSeq - NC_000019.10
RefSeq - NG_052633.1
RefSeq - NW_003571056.2
RefSeq - NW_003571057.2
RefSeq - NW_003571058.2
RefSeq - NW_003571059.2
RefSeq - NW_003571060.1
RefSeq - 1126514972
RefSeq - NP_001167552.1
RefSeq - NP_001167553.1
RefSeq - NP_001167554.1
RefSeq - NP_001334932.1
RefSeq - NP_060322.1
RefSeq - NT_187693.1
RefSeq - NW_003571054.1
RefSeq - NW_003571055.2
RefSeq - NM_001174081.2
RefSeq - NM_001174082.2
RefSeq - NM_001174083.1
RefSeq - NM_001348003.1
RefSeq - NM_017852.4
RefSeq - NR_145325.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000022556 to get all the annotations available for this gene.


Gene Ontology (GO)
cell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathresponse to stressnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processimmune responsemacromolecule localizationestablishment of localizationcytokine productioncell deathcell deathresponse toresponse to stressnitrogen conitrogen compound metabolic processbiosynthetibiosynthetic processcellular mecellular metabolic processprimary metprimary metabolic processregulation regulation of molecular functionorganic suborganic substance metabolic processimmune respimmune responsemacromolecumacromolecule localizationestablishmeestablishment of localizationcytokine prcytokine production
protein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingprotein bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingdrug bindingdrug binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IGI
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0032090 Pyrin domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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