55737


Homo sapiens (NCBI)

Features
Gene ID: 55737
  
Biological name :
  
Synonyms : MEM3|PARK17 / VPS35 / VPS35, retromer complex component
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1561146_at (Human Genome U133 Plus 2.0 Array)   217727_x_at (Human Genome U133 Plus 2.0 Array)   222387_s_at (Human Genome U133 Plus 2.0 Array)   222388_s_at (Human Genome U133 Plus 2.0 Array)   233864_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 17999541
RefSeq - 530424105
RefSeq - 767990260
RefSeq - NC_000016.10
RefSeq - NG_029970.1
RefSeq - NP_060676.2
RefSeq - XP_005256102.1
RefSeq - XP_011521529.1
RefSeq - NM_018206.5
RefSeq - XM_011523227.3
RefSeq - XM_005256045.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000069329 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010821 regulation of mitochondrion organization IGI
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032268 regulation of cellular protein metabolic process IGI
 biological_processGO:0032463 negative regulation of protein homooligomerization IEA
 biological_processGO:0033365 protein localization to organelle IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi NAS
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IMP
 biological_processGO:0045056 transcytosis IDA
 biological_processGO:0050728 negative regulation of inflammatory response IGI
 biological_processGO:0050882 voluntary musculoskeletal movement IEA
 biological_processGO:0060161 positive regulation of dopamine receptor signaling pathway IDA
 biological_processGO:0060548 negative regulation of cell death IGI
 biological_processGO:0061357 positive regulation of Wnt protein secretion IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission IMP
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090326 positive regulation of locomotion involved in locomotory behavior IEA
 biological_processGO:0099074 mitochondrion to lysosome transport IMP
 biological_processGO:0099639 neurotransmitter receptor transport, endosome to plasma membrane IDA
 biological_processGO:1901215 negative regulation of neuron death IGI
 biological_processGO:1902823 negative regulation of late endosome to lysosome transport IMP
 biological_processGO:1902950 regulation of dendritic spine maintenance IMP
 biological_processGO:1903181 positive regulation of dopamine biosynthetic process IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IGI
 biological_processGO:1903828 negative regulation of cellular protein localization IEA
 biological_processGO:1905166 negative regulation of lysosomal protein catabolic process IEA
 biological_processGO:1905606 regulation of presynapse assembly ISS
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IMP
 biological_processGO:2000331 regulation of terminal button organization IMP
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005770 late endosome IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030904 retromer complex TAS
 cellular_componentGO:0030906 retromer, cargo-selective complex NAS
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097422 tubular endosome IDA
 cellular_componentGO:0099073 mitochondrion-derived vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0031748 D1 dopamine receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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