5578


Homo sapiens (NCBI)

Features
Gene ID: 5578
  
Biological name :
  
Synonyms : AAG6|PKC-alpha|PKCA|PRKACA / PRKCA / protein kinase C alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1560074_at (Human Genome U133 Plus 2.0 Array)   206923_at (Human Genome U133 Plus 2.0 Array)   213093_at (Human Genome U133 Plus 2.0 Array)   215194_at (Human Genome U133 Plus 2.0 Array)   215195_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000017.11
RefSeq - XP_016880325.1
RefSeq - XP_016880326.1
RefSeq - XP_016880330.1
RefSeq - XP_024306597.1
RefSeq - XP_024306598.1
RefSeq - 1034600418
RefSeq - NG_012206.1
RefSeq - 1034600420
RefSeq - NP_002728.1
RefSeq - 1034600428
RefSeq - 1370471576
RefSeq - 1370471578
RefSeq - 4506067
RefSeq - XR_001752558.1
RefSeq - NM_002737.2
RefSeq - XM_017024836.2
RefSeq - XM_017024837.1
RefSeq - XM_017024841.1
RefSeq - XM_024450829.1
RefSeq - XM_024450830.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000154229 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0002159 desmosome assembly IMP
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISS
 biological_processGO:0018105 peptidyl-serine phosphorylation TAS
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISS
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0034351 negative regulation of glial cell apoptotic process IMP
 biological_processGO:0035408 histone H3-T6 phosphorylation IDA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0045651 positive regulation of macrophage differentiation ISS
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045780 positive regulation of bone resorption ISS
 biological_processGO:0045785 positive regulation of cell adhesion IMP
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0070555 response to interleukin-1 IMP
 biological_processGO:0090330 regulation of platelet aggregation IDA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 biological_processGO:0106071 positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway ISS
 biological_processGO:2000707 positive regulation of dense core granule biogenesis ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion HDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0035866 alphav-beta3 integrin-PKCalpha complex ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004697 protein kinase C activity TAS
 molecular_functionGO:0004698 calcium-dependent protein kinase C activity TAS
 molecular_functionGO:0005178 integrin binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IDA
 molecular_functionGO:0035403 histone kinase activity (H3-T6 specific) IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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