5590


Homo sapiens (NCBI)

Features
Gene ID: 5590
  
Biological name :
  
Synonyms : PKC-ZETA|PKC2 / PRKCZ / protein kinase C zeta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1569748_at (Human Genome U133 Plus 2.0 Array)   202178_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 52486327
RefSeq - 75709226
RefSeq - 75709228
RefSeq - 767905117
RefSeq - 767905120
RefSeq - 767905122
RefSeq - 767905124
RefSeq - NC_000001.11
RefSeq - NG_029616.1
RefSeq - XP_011540075.1
RefSeq - XP_011540076.1
RefSeq - XP_011540077.1
RefSeq - XP_011540078.1
RefSeq - XP_016857278.1
RefSeq - XP_016857279.1
RefSeq - XP_016857281.1
RefSeq - XP_016857282.1
RefSeq - XP_016857286.1
RefSeq - XP_016857289.1
RefSeq - XP_016857290.1
RefSeq - XP_016857291.1
RefSeq - XP_016857292.1
RefSeq - XP_024304158.1
RefSeq - XP_024304159.1
RefSeq - XP_024304164.1
RefSeq - XP_024304165.1
RefSeq - 1034560172
RefSeq - 1034560177
RefSeq - 1034560170
RefSeq - 1034560179
RefSeq - 1034560187
RefSeq - 1034560194
RefSeq - 1034560196
RefSeq - 1034560198
RefSeq - 1034560200
RefSeq - NP_001028753.1
RefSeq - NP_001028754.1
RefSeq - NP_001229803.1
RefSeq - NP_001337732.1
RefSeq - NP_001337733.1
RefSeq - NP_001337734.1
RefSeq - NP_001337735.1
RefSeq - NP_002735.3
RefSeq - 1185542384
RefSeq - 1185542386
RefSeq - 1185542388
RefSeq - 1185542390
RefSeq - 1370453929
RefSeq - 1370453931
RefSeq - 1370453934
RefSeq - 1370453936
RefSeq - 338968874
RefSeq - XR_002957131.1
RefSeq - NM_001033581.2
RefSeq - NM_001033582.2
RefSeq - NM_001242874.2
RefSeq - NM_001350803.1
RefSeq - NM_001350804.1
RefSeq - NM_001350805.1
RefSeq - NM_001350806.1
RefSeq - NM_002744.5
RefSeq - NR_146911.1
RefSeq - XM_011541773.1
RefSeq - XM_011541774.1
RefSeq - XM_011541775.3
RefSeq - XM_011541776.1
RefSeq - XM_017001789.1
RefSeq - XM_017001790.1
RefSeq - XM_017001792.1
RefSeq - XM_017001793.1
RefSeq - XM_017001797.1
RefSeq - XM_017001800.1
RefSeq - XM_017001801.1
RefSeq - XM_017001802.1
RefSeq - XM_017001803.2
RefSeq - XM_024448390.1
RefSeq - XM_024448391.1
RefSeq - XM_024448396.1
RefSeq - XM_024448397.1
RefSeq - XR_001737315.2
RefSeq - XR_002957130.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000067606 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0030010 establishment of cell polarity ISS
 biological_processGO:0031333 negative regulation of protein complex assembly IMP
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0031584 activation of phospholipase D activity IEA
 biological_processGO:0032148 activation of protein kinase B activity IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production ISS
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045630 positive regulation of T-helper 2 cell differentiation ISS
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IMP
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway ISS
 biological_processGO:0047496 vesicle transport along microtubule IEA
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051346 negative regulation of hydrolase activity IEA
 biological_processGO:0051899 membrane depolarization IEA
 biological_processGO:0060081 membrane hyperpolarization IEA
 biological_processGO:0060291 long-term synaptic potentiation ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070528 protein kinase C signaling IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:1990138 neuron projection extension IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential ISS
 biological_processGO:2000553 positive regulation of T-helper 2 cell cytokine production ISS
 biological_processGO:2000664 positive regulation of interleukin-5 secretion ISS
 biological_processGO:2000667 positive regulation of interleukin-13 secretion ISS
 biological_processGO:2001181 positive regulation of interleukin-10 secretion ISS
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0030054 cell junction TAS
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0035748 myelin sheath abaxonal region IEA
 cellular_componentGO:0043203 axon hillock IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045179 apical cortex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004697 protein kinase C activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015459 potassium channel regulator activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043274 phospholipase binding IEA
 molecular_functionGO:0043560 insulin receptor substrate binding IC
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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