5605


Homo sapiens (NCBI)

Features
Gene ID: 5605
  
Biological name :
  
Synonyms : CFC4|MAPKK2|MEK2|MKK2|PRKMK2 / MAP2K2 / mitogen-activated protein kinase kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202424_at (Human Genome U133 Plus 2.0 Array)   213487_at (Human Genome U133 Plus 2.0 Array)   213490_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016882480.1
RefSeq - 1034608530
RefSeq - 1034608532
RefSeq - 13489054
RefSeq - 578833393
RefSeq - NC_000019.10
RefSeq - NG_007996.1
RefSeq - NP_109587.1
RefSeq - XP_006722862.1
RefSeq - XP_016882478.1
RefSeq - XP_016882479.1
RefSeq - 1034608528
RefSeq - NM_030662.3
RefSeq - XM_017026991.1
RefSeq - XM_006722799.2
RefSeq - XM_017026989.1
RefSeq - XM_017026990.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000126934 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0010629 negative regulation of gene expression IGI
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0032872 regulation of stress-activated MAPK cascade TAS
 biological_processGO:0036289 peptidyl-serine autophosphorylation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0070371 ERK1 and ERK2 cascade TAS
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0090170 regulation of Golgi inheritance TAS
 biological_processGO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA IMP
 biological_processGO:2000641 regulation of early endosome to late endosome transport TAS
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0005770 late endosome TAS
 cellular_componentGO:0005778 peroxisomal membrane HDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005925 focal adhesion TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004708 MAP kinase kinase activity IDA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030165 PDZ domain binding IDA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0097110 scaffold protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr