5607


Homo sapiens (NCBI)

Features
Gene ID: 5607
  
Biological name :
  
Synonyms : HsT17454|MAPKK5|MEK5|PRKMK5 / MAP2K5 / mitogen-activated protein kinase kinase 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204756_at (Human Genome U133 Plus 2.0 Array)   210482_x_at (Human Genome U133 Plus 2.0 Array)   211370_s_at (Human Genome U133 Plus 2.0 Array)   211371_at (Human Genome U133 Plus 2.0 Array)   216435_at (Human Genome U133 Plus 2.0 Array)   216765_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_660143.1
RefSeq - 767984716
RefSeq - NC_000015.10
RefSeq - NG_029143.1
RefSeq - 1370466952
RefSeq - XP_011520089.1
RefSeq - XP_011520090.1
RefSeq - XP_016877903.1
RefSeq - XP_024305756.1
RefSeq - 1034591310
RefSeq - 21729895
RefSeq - 332164798
RefSeq - 4506101
RefSeq - 767984714
RefSeq - NP_001193733.1
RefSeq - NP_002748.1
RefSeq - XR_001751355.2
RefSeq - NM_001206804.1
RefSeq - NM_002757.3
RefSeq - NM_145160.2
RefSeq - NM_145161.1
RefSeq - NM_145162.1
RefSeq - XM_011521787.3
RefSeq - XM_011521788.3
RefSeq - XM_017022414.2
RefSeq - XM_024449988.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137764 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0000187 activation of MAPK activity ISS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion ISS
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISS
 biological_processGO:0045415 negative regulation of interleukin-8 biosynthetic process ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0051247 positive regulation of protein metabolic process ISS
 biological_processGO:0060761 negative regulation of response to cytokine stimulus ISS
 biological_processGO:0070375 ERK5 cascade IEA
 biological_processGO:0071363 cellular response to growth factor stimulus ISS
 biological_processGO:0071499 cellular response to laminar fluid shear stress TAS
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis ISS
 biological_processGO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production ISS
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004708 MAP kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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