5621


Homo sapiens (NCBI)

Features
Gene ID: 5621
  
Biological name :
  
Synonyms : ASCR|AltPrP|CD230|CJD|GSS|KURU|PRIP|PrP|PrP27-30|PrP33-35C|PrPc|p27-30 / prion protein / PRNP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201300_s_at (Human Genome U133 Plus 2.0 Array)   215707_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 122056623
RefSeq - 122056625
RefSeq - 122056628
RefSeq - 34335270
RefSeq - 409104118
RefSeq - 4506113
RefSeq - NC_000020.11
RefSeq - NG_009087.1
RefSeq - NP_000302.1
RefSeq - NP_001073590.1
RefSeq - NP_001073591.1
RefSeq - NP_001073592.1
RefSeq - NP_001258490.1
RefSeq - NP_898902.1
RefSeq - NM_000311.4
RefSeq - NM_001080121.2
RefSeq - NM_001080122.2
RefSeq - NM_001080123.2
RefSeq - NM_001271561.2
RefSeq - NM_183079.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000171867 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation ISS
 biological_processGO:0006878 cellular copper ion homeostasis NAS
 biological_processGO:0006979 response to oxidative stress ISS
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007611 learning or memory ISS
 biological_processGO:0007616 long-term memory TAS
 biological_processGO:0010955 negative regulation of protein processing TAS
 biological_processGO:0031648 protein destabilization IMP
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production ISS
 biological_processGO:0032700 negative regulation of interleukin-17 production ISS
 biological_processGO:0032703 negative regulation of interleukin-2 production ISS
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IGI
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity ISS
 biological_processGO:0043525 positive regulation of neuron apoptotic process IMP
 biological_processGO:0046007 negative regulation of activated T cell proliferation ISS
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation ISS
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway ISS
 biological_processGO:0051260 protein homooligomerization IMP
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IGI
 biological_processGO:0070885 negative regulation of calcineurin-NFAT signaling cascade ISS
 biological_processGO:0071280 cellular response to copper ion IDA
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 biological_processGO:0090647 modulation of age-related behavioral decline ISS
 biological_processGO:0097062 dendritic spine maintenance TAS
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation IEA
 biological_processGO:1900449 regulation of glutamate receptor signaling pathway ISS
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1901379 regulation of potassium ion transmembrane transport IEA
 biological_processGO:1902430 negative regulation of amyloid-beta formation ISS
 biological_processGO:1902938 regulation of intracellular calcium activated chloride channel activity IGI
 biological_processGO:1902951 negative regulation of dendritic spine maintenance ISS
 biological_processGO:1902992 negative regulation of amyloid precursor protein catabolic process ISS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:1904645 response to amyloid-beta ISS
 biological_processGO:1904646 cellular response to amyloid-beta IGI
 biological_processGO:1905664 regulation of calcium ion import across plasma membrane ISS
 biological_processGO:1990535 neuron projection maintenance ISS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0014069 postsynaptic density TAS
 cellular_componentGO:0016234 inclusion body IMP
 cellular_componentGO:0019898 extrinsic component of membrane TAS
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane NAS
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045121 membrane raft ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0098794 postsynapse TAS
 molecular_functionGO:0001540 amyloid-beta binding TAS
 molecular_functionGO:0002020 protease binding ISS
 molecular_functionGO:0005507 copper ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005521 lamin binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding ISS
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0015631 tubulin binding IDA
 molecular_functionGO:0031802 type 5 metabotropic glutamate receptor binding ISS
 molecular_functionGO:0031805 type 8 metabotropic glutamate receptor binding IDA
 molecular_functionGO:0038023 signaling receptor activity ISS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043008 ATP-dependent protein binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0044877 protein-containing complex binding ISS
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:1903135 cupric ion binding IEA
 molecular_functionGO:1903136 cuprous ion binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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