5629


Homo sapiens (NCBI)

Features
Gene ID: 5629
  
Biological name :
  
Synonyms : prospero homeobox 1 / PROX1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207401_at (Human Genome U133 Plus 2.0 Array)   228656_at (Human Genome U133 Plus 2.0 Array)   229376_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034560277
RefSeq - 1034560279
RefSeq - 21359846
RefSeq - 397174762
RefSeq - 530366332
RefSeq - 530366334
RefSeq - 767909898
RefSeq - 767909901
RefSeq - 767909903
RefSeq - NC_000001.11
RefSeq - NP_001257545.1
RefSeq - NP_002754.2
RefSeq - XP_005273251.1
RefSeq - XP_005273252.1
RefSeq - XP_011508073.1
RefSeq - XP_011508074.1
RefSeq - XP_011508075.1
RefSeq - XP_016857321.1
RefSeq - XP_016857322.1
RefSeq - NM_001270616.1
RefSeq - NM_002763.4
RefSeq - XM_017001832.1
RefSeq - XM_017001833.1
RefSeq - XM_005273194.2
RefSeq - XM_005273195.4
RefSeq - XM_011509771.1
RefSeq - XM_011509772.2
RefSeq - XM_011509773.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000117707 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001822 kidney development IEP
 biological_processGO:0001889 liver development IEP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0001946 lymphangiogenesis IDA
 biological_processGO:0002088 lens development in camera-type eye IEP
 biological_processGO:0002194 hepatocyte cell migration IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEP
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010468 regulation of gene expression IDA
 biological_processGO:0010595 positive regulation of endothelial cell migration IDA
 biological_processGO:0021516 dorsal spinal cord development ISS
 biological_processGO:0021542 dentate gyrus development ISS
 biological_processGO:0021707 cerebellar granule cell differentiation ISS
 biological_processGO:0021915 neural tube development ISS
 biological_processGO:0030240 skeletal muscle thin filament assembly ISS
 biological_processGO:0030324 lung development IEP
 biological_processGO:0030910 olfactory placode formation ISS
 biological_processGO:0031016 pancreas development IEP
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0042752 regulation of circadian rhythm IMP
 biological_processGO:0043049 otic placode formation ISS
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0045787 positive regulation of cell cycle ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0046619 optic placode formation involved in camera-type eye formation ISS
 biological_processGO:0048845 venous blood vessel morphogenesis ISS
 biological_processGO:0055005 ventricular cardiac myofibril assembly ISS
 biological_processGO:0055009 atrial cardiac muscle tissue morphogenesis ISS
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis ISS
 biological_processGO:0060042 retina morphogenesis in camera-type eye ISS
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IEP
 biological_processGO:0060214 endocardium formation ISS
 biological_processGO:0060298 positive regulation of sarcomere organization ISS
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060414 aorta smooth muscle tissue morphogenesis ISS
 biological_processGO:0060421 positive regulation of heart growth ISS
 biological_processGO:0060836 lymphatic endothelial cell differentiation IDA
 biological_processGO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment IMP
 biological_processGO:0061114 branching involved in pancreas morphogenesis IEA
 biological_processGO:0070309 lens fiber cell morphogenesis IEP
 biological_processGO:0070365 hepatocyte differentiation IEP
 biological_processGO:0070858 negative regulation of bile acid biosynthetic process IMP
 biological_processGO:0072574 hepatocyte proliferation IEA
 biological_processGO:0090425 acinar cell differentiation IEA
 biological_processGO:0097150 neuronal stem cell population maintenance ISS
 biological_processGO:1901978 positive regulation of cell cycle checkpoint IEA
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation ISS
 biological_processGO:2000979 positive regulation of forebrain neuron differentiation ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003700 DNA-binding transcription factor activity IC
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ISS
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016922 nuclear receptor binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0050692 DBD domain binding IPI
 molecular_functionGO:0050693 LBD domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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