56928


Homo sapiens (NCBI)
membraneproteinproteolysisregulationintegralcomponentsideendoplasmicreticulumactivitysignalpeptideprocessingectodomaintumornecrosisfactor-mediatedsignalingpathwayintracellulardomainimmuneresponsegolginucleoplasmlysosomalcentrosomeplasmaendosomeactin

Features
Gene ID: 56928
  
Biological name :
  
Synonyms : IMP-4|IMP4|PSH4|PSL1 / signal peptide peptidase like 2B / SPPL2B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210693_at (Human Genome U133 Plus 2.0 Array)   215833_s_at (Human Genome U133 Plus 2.0 Array)   225248_at (Human Genome U133 Plus 2.0 Array)   225249_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 768003159
RefSeq - NC_000019.10
RefSeq - XP_011526440.1
RefSeq - XP_011526441.1
RefSeq - XP_011526442.1
RefSeq - XP_016882505.1
RefSeq - XP_016882506.1
RefSeq - XP_016882507.1
RefSeq - XP_016882508.1
RefSeq - XP_024307387.1
RefSeq - NG_032984.1
RefSeq - 1034608600
RefSeq - 1034608602
RefSeq - NP_001070706.1
RefSeq - 1034608598
RefSeq - NP_694533.1
RefSeq - 1034608605
RefSeq - 116734691
RefSeq - 1370475547
RefSeq - 41281782
RefSeq - 768003151
RefSeq - 768003155
RefSeq - XR_002958334.1
RefSeq - NM_001077238.1
RefSeq - NM_152988.2
RefSeq - XM_011528138.2
RefSeq - XM_011528139.2
RefSeq - XM_011528140.1
RefSeq - XM_017027016.1
RefSeq - XM_017027017.1
RefSeq - XM_017027018.2
RefSeq - XM_017027019.1
RefSeq - XM_024451619.1
RefSeq - XR_001753719.1
RefSeq - XR_001753720.2
RefSeq - XR_001753721.1
RefSeq - XR_001753722.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000005206 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to chemicalcellular response to stimulusimmune responsenitrogen compoundnitrogen compound metabolic processcellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processcell communicatiocell communicationresponse to chemiresponse to chemicalcellular responsecellular response to stimulusimmune responseimmune response
protein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingprotein bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activity
cellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellcellmembranemembraneorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing IBA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IDA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0031293 membrane protein intracellular domain proteolysis IMP
 biological_processGO:0033619 membrane protein proteolysis IDA
 biological_processGO:0050776 regulation of immune response IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005765 lysosomal membrane IDA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IDA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IDA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving TAS
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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