57154


Homo sapiens (NCBI)

Features
Gene ID: 57154
  
Biological name :
  
Synonyms : SMAD specific E3 ubiquitin protein ligase 1 / SMURF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212666_at (Human Genome U133 Plus 2.0 Array)   212668_at (Human Genome U133 Plus 2.0 Array)   215458_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034656352
RefSeq - 31317290
RefSeq - 31317292
RefSeq - 315434204
RefSeq - NC_000007.14
RefSeq - NP_065162.1
RefSeq - NP_851994.1
RefSeq - NW_017852929.1
RefSeq - XP_016867946.1
RefSeq - NP_001186776.1
RefSeq - NM_001199847.1
RefSeq - NM_020429.2
RefSeq - NM_181349.2
RefSeq - XM_017012457.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198742 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006611 protein export from nucleus IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007398 ectoderm development TAS
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0030154 cell differentiation IDA
 biological_processGO:0030279 negative regulation of ossification IEA
 biological_processGO:0030509 BMP signaling pathway TAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0030514 negative regulation of BMP signaling pathway TAS
 biological_processGO:0030579 ubiquitin-dependent SMAD protein catabolic process IDA
 biological_processGO:0032801 receptor catabolic process IDA
 biological_processGO:0034394 protein localization to cell surface IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0045732 positive regulation of protein catabolic process IBA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway TAS
 biological_processGO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization IEA
 biological_processGO:0061736 engulfment of target by autophagosome IMP
 biological_processGO:0061753 substrate localization to autophagosome IMP
 biological_processGO:0071211 protein targeting to vacuole involved in autophagy IMP
 biological_processGO:0072659 protein localization to plasma membrane TAS
 biological_processGO:1903861 positive regulation of dendrite extension IDA
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IMP
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IGI
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding TAS
 molecular_functionGO:0048185 activin binding NAS
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS
 molecular_functionGO:0070411 I-SMAD binding IPI
 molecular_functionGO:0070412 R-SMAD binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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