57320


Mus musculus (NCBI)

Features
Gene ID: 57320
  
Biological name :
  
Synonyms : DJ-1|Dj1 / Park7 / Parkinson disease (autosomal recessive, early onset) 7
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416526_a_at (Mouse Genome 430 2.0 Array)   1456194_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 55741460
RefSeq - NC_000070.6
RefSeq - NP_065594.2
RefSeq - NT_187025.1
RefSeq - NM_020569.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000028964 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001963 synaptic transmission, dopaminergic IMP
 biological_processGO:0002866 positive regulation of acute inflammatory response to antigenic stimulus IMP
 biological_processGO:0006281 DNA repair ISO
 biological_processGO:0006469 negative regulation of protein kinase activity ISO
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006979 response to oxidative stress ISO
 biological_processGO:0007005 mitochondrion organization IMP
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008344 adult locomotory behavior IMP
 biological_processGO:0010273 detoxification of copper ion ISO
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0018323 enzyme active site formation via L-cysteine sulfinic acid IMP
 biological_processGO:0019249 lactate biosynthetic process ISO
 biological_processGO:0030073 insulin secretion IMP
 biological_processGO:0031397 negative regulation of protein ubiquitination ISO
 biological_processGO:0032091 negative regulation of protein binding ISO
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0032757 positive regulation of interleukin-8 production ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation ISO
 biological_processGO:0033234 negative regulation of protein sumoylation ISO
 biological_processGO:0033864 positive regulation of NAD(P)H oxidase activity IMP
 biological_processGO:0034599 cellular response to oxidative stress ISO
 biological_processGO:0034614 cellular response to reactive oxygen species IMP
 biological_processGO:0036471 cellular response to glyoxal ISO
 biological_processGO:0036526 peptidyl-cysteine deglycation ISO
 biological_processGO:0036527 peptidyl-arginine deglycation ISO
 biological_processGO:0036528 peptidyl-lysine deglycation ISO
 biological_processGO:0036529 protein deglycation, glyoxal removal ISO
 biological_processGO:0036531 glutathione deglycation ISO
 biological_processGO:0042177 negative regulation of protein catabolic process IMP
 biological_processGO:0042542 response to hydrogen peroxide IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0042743 hydrogen peroxide metabolic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043523 regulation of neuron apoptotic process ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046295 glycolate biosynthetic process ISO
 biological_processGO:0046826 negative regulation of protein export from nucleus ISO
 biological_processGO:0050727 regulation of inflammatory response IMP
 biological_processGO:0050787 detoxification of mercury ion ISO
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051444 negative regulation of ubiquitin-protein transferase activity ISO
 biological_processGO:0051583 dopamine uptake involved in synaptic transmission IMP
 biological_processGO:0051881 regulation of mitochondrial membrane potential ISO
 biological_processGO:0051899 membrane depolarization IMP
 biological_processGO:0060081 membrane hyperpolarization IMP
 biological_processGO:0060548 negative regulation of cell death ISO
 biological_processGO:0060765 regulation of androgen receptor signaling pathway ISO
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0090073 positive regulation of protein homodimerization activity ISO
 biological_processGO:0106044 guanine deglycation ISO
 biological_processGO:0106045 guanine deglycation, methylglyoxal removal ISO
 biological_processGO:0106046 guanine deglycation, glyoxal removal ISO
 biological_processGO:1900182 positive regulation of protein localization to nucleus ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1901671 positive regulation of superoxide dismutase activity ISO
 biological_processGO:1901984 negative regulation of protein acetylation ISO
 biological_processGO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IMP
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ISO
 biological_processGO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone ISO
 biological_processGO:1903094 negative regulation of protein K48-linked deubiquitination ISO
 biological_processGO:1903122 negative regulation of TRAIL-activated apoptotic signaling pathway ISO
 biological_processGO:1903168 positive regulation of pyrroline-5-carboxylate reductase activity ISO
 biological_processGO:1903178 positive regulation of tyrosine 3-monooxygenase activity ISO
 biological_processGO:1903181 positive regulation of dopamine biosynthetic process ISO
 biological_processGO:1903189 glyoxal metabolic process ISO
 biological_processGO:1903197 positive regulation of L-dopa biosynthetic process ISO
 biological_processGO:1903200 positive regulation of L-dopa decarboxylase activity ISO
 biological_processGO:1903202 negative regulation of oxidative stress-induced cell death ISO
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IMP
 biological_processGO:1903206 negative regulation of hydrogen peroxide-induced cell death ISO
 biological_processGO:1903208 negative regulation of hydrogen peroxide-induced neuron death ISO
 biological_processGO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway ISO
 biological_processGO:1903384 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway ISO
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process IMP
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process IDA
 biological_processGO:1904782 negative regulation of NMDA glutamate receptor activity ISO
 biological_processGO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway ISO
 biological_processGO:1905516 positive regulation of fertilization ISO
 biological_processGO:2000157 negative regulation of ubiquitin-specific protease activity ISO
 biological_processGO:2000277 positive regulation of oxidative phosphorylation uncoupler activity IMP
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding ISO
 biological_processGO:2000825 positive regulation of androgen receptor activity ISO
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway ISO
 biological_processGO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ISO
 cellular_componentGO:0000785 chromatin ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space IDA
 cellular_componentGO:0005759 mitochondrial matrix IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016605 PML body ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0044297 cell body IDA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0061827 sperm head ISO
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005507 copper ion binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0008233 peptidase activity ISO
 molecular_functionGO:0016532 superoxide dismutase copper chaperone activity ISO
 molecular_functionGO:0016684 oxidoreductase activity, acting on peroxide as acceptor ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019900 kinase binding ISO
 molecular_functionGO:0019955 cytokine binding ISO
 molecular_functionGO:0036470 tyrosine 3-monooxygenase activator activity ISO
 molecular_functionGO:0036478 L-dopa decarboxylase activator activity ISO
 molecular_functionGO:0036524 protein deglycase activity ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044388 small protein activating enzyme binding ISO
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding ISO
 molecular_functionGO:0045340 mercury ion binding ISO
 molecular_functionGO:0050681 androgen receptor binding ISO
 molecular_functionGO:0051920 peroxiredoxin activity IMP
 molecular_functionGO:0070491 repressing transcription factor binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO
 molecular_functionGO:1903135 cupric ion binding ISO
 molecular_functionGO:1903136 cuprous ion binding ISO
 molecular_functionGO:1990381 ubiquitin-specific protease binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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