5740


Homo sapiens (NCBI)

Features
Gene ID: 5740
  
Biological name :
  
Synonyms : CYP8|CYP8A1|PGIS|PTGI / prostaglandin I2 synthase / PTGIS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208131_s_at (Human Genome U133 Plus 2.0 Array)   210702_s_at (Human Genome U133 Plus 2.0 Array)   211892_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 13699859
RefSeq - NC_000020.11
RefSeq - NG_007940.1
RefSeq - NP_000952.1
RefSeq - NM_000961.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000124212 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IDA
 biological_processGO:0006690 icosanoid metabolic process TAS
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0019371 cyclooxygenase pathway TAS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway TAS
 biological_processGO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0045019 negative regulation of nitric oxide biosynthetic process IDA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0046697 decidualization IEA
 biological_processGO:0050728 negative regulation of inflammatory response IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEP
 biological_processGO:0071354 cellular response to interleukin-6 IEP
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:0097190 apoptotic signaling pathway IDA
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IDA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008116 prostaglandin-I synthase activity TAS
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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