5747


Homo sapiens (NCBI)

Features
Gene ID: 5747
  
Biological name :
  
Synonyms : FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK / protein tyrosine kinase 2 / PTK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1559529_at (Human Genome U133 Plus 2.0 Array)   207821_s_at (Human Genome U133 Plus 2.0 Array)   208820_at (Human Genome U133 Plus 2.0 Array)   241453_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1208915076
RefSeq - 1034660971
RefSeq - 1034660975
RefSeq - 1034660977
RefSeq - 1034660994
RefSeq - 1034660998
RefSeq - 1034661004
RefSeq - 1034661037
RefSeq - 1034661045
RefSeq - 1208914887
RefSeq - 1208914895
RefSeq - 1208914897
RefSeq - 1208914899
RefSeq - 1208914901
RefSeq - 1208914903
RefSeq - 1208914905
RefSeq - 1208914907
RefSeq - 1208914909
RefSeq - 1208914911
RefSeq - 1208914913
RefSeq - 1208914915
RefSeq - 1208914919
RefSeq - 1208914921
RefSeq - 1208914924
RefSeq - 1208914926
RefSeq - 1208914928
RefSeq - 1208914930
RefSeq - 1208914934
RefSeq - 1208914940
RefSeq - 1208914944
RefSeq - 1208914946
RefSeq - 1208914950
RefSeq - 1208914952
RefSeq - 1208914956
RefSeq - 1208914966
RefSeq - 1208914968
RefSeq - 1208914974
RefSeq - 1208914980
RefSeq - 1208914984
RefSeq - 1208914986
RefSeq - 1208914990
RefSeq - 1208914992
RefSeq - 1208914994
RefSeq - 1208915000
RefSeq - 1208915004
RefSeq - 1208915006
RefSeq - 1208915010
RefSeq - 1208915015
RefSeq - 1208915019
RefSeq - 1208915023
RefSeq - 1208915027
RefSeq - 1208915029
RefSeq - 1208915031
RefSeq - 1208915037
RefSeq - 1208915039
RefSeq - 1208915042
RefSeq - 1208915044
RefSeq - 1208915048
RefSeq - 1208915054
RefSeq - 1208915058
RefSeq - 1208915060
RefSeq - 1208915062
RefSeq - 1208915064
RefSeq - 1208915068
RefSeq - 1208915070
RefSeq - 1208915074
RefSeq - 1034660969
RefSeq - 1209050337
RefSeq - 1370512615
RefSeq - 1370512617
RefSeq - 1370512619
RefSeq - 1370512622
RefSeq - 1370512624
RefSeq - 1370512626
RefSeq - 1370512629
RefSeq - 1370512633
RefSeq - 1370512635
RefSeq - 1370512637
RefSeq - 1370512639
RefSeq - 1370512641
RefSeq - 1370512645
RefSeq - 1370512648
RefSeq - 24476013
RefSeq - 27886593
RefSeq - 313851044
RefSeq - 939106606
RefSeq - NC_000008.11
RefSeq - NG_029467.1
RefSeq - NP_001186578.1
RefSeq - NP_001303271.1
RefSeq - NP_001339623.1
RefSeq - NP_001339624.1
RefSeq - NP_001339625.1
RefSeq - NP_001339626.1
RefSeq - NP_001339627.1
RefSeq - NP_001339628.1
RefSeq - NP_001339629.1
RefSeq - NP_001339630.1
RefSeq - NP_001339631.1
RefSeq - NP_001339632.1
RefSeq - NP_001339633.1
RefSeq - NP_001339634.1
RefSeq - NP_001339635.1
RefSeq - NP_001339636.1
RefSeq - NP_001339637.1
RefSeq - NP_001339638.1
RefSeq - NP_001339639.1
RefSeq - NP_001339640.1
RefSeq - NP_001339641.1
RefSeq - NP_001339642.1
RefSeq - NP_001339643.1
RefSeq - NP_001339644.1
RefSeq - NP_001339645.1
RefSeq - NP_001339646.1
RefSeq - NP_001339647.1
RefSeq - NP_001339648.1
RefSeq - NP_001339649.1
RefSeq - NP_001339650.1
RefSeq - NP_001339651.1
RefSeq - NP_001339652.1
RefSeq - NP_001339653.1
RefSeq - NP_001339654.1
RefSeq - NP_001339655.1
RefSeq - NP_001339656.1
RefSeq - NP_001339657.1
RefSeq - NP_001339658.1
RefSeq - NP_001339659.1
RefSeq - NP_001339660.1
RefSeq - NP_001339661.1
RefSeq - NP_001339662.1
RefSeq - NP_001339663.1
RefSeq - NP_001339664.1
RefSeq - NP_001339665.1
RefSeq - NP_001339666.1
RefSeq - NP_001339667.1
RefSeq - NP_001339668.1
RefSeq - NP_001339669.1
RefSeq - NP_001339670.1
RefSeq - NP_001339671.1
RefSeq - NP_001339672.1
RefSeq - NP_001339673.1
RefSeq - NP_001339674.1
RefSeq - NP_001339675.1
RefSeq - NP_001339676.1
RefSeq - NP_001339677.1
RefSeq - NP_001339678.1
RefSeq - NP_001339679.1
RefSeq - NP_001339680.1
RefSeq - NP_001339681.1
RefSeq - NP_005598.3
RefSeq - NP_722560.1
RefSeq - XP_016869142.1
RefSeq - XP_016869143.1
RefSeq - XP_016869145.1
RefSeq - XP_016869146.1
RefSeq - XP_016869153.1
RefSeq - XP_016869155.1
RefSeq - XP_016869158.1
RefSeq - XP_016869173.1
RefSeq - XP_016869177.1
RefSeq - XP_024302967.1
RefSeq - XP_024302968.1
RefSeq - XP_024302969.1
RefSeq - XP_024302970.1
RefSeq - XP_024302971.1
RefSeq - XP_024302972.1
RefSeq - XP_024302973.1
RefSeq - XP_024302974.1
RefSeq - XP_024302975.1
RefSeq - XP_024302976.1
RefSeq - XP_024302977.1
RefSeq - XP_024302978.1
RefSeq - XP_024302979.1
RefSeq - XP_024302980.1
RefSeq - XM_024447200.1
RefSeq - XM_024447201.1
RefSeq - XM_024447202.1
RefSeq - XM_024447203.1
RefSeq - NM_001199649.1
RefSeq - NM_001316342.1
RefSeq - NM_001352694.1
RefSeq - NM_001352695.1
RefSeq - NM_001352696.1
RefSeq - NM_001352697.1
RefSeq - NM_001352698.1
RefSeq - NM_001352699.1
RefSeq - NM_001352700.1
RefSeq - NM_001352701.1
RefSeq - NM_001352702.1
RefSeq - NM_001352703.1
RefSeq - NM_001352704.1
RefSeq - NM_001352705.1
RefSeq - NM_001352706.1
RefSeq - NM_001352707.1
RefSeq - NM_001352708.1
RefSeq - NM_001352709.1
RefSeq - NM_001352710.1
RefSeq - NM_001352711.1
RefSeq - NM_001352712.1
RefSeq - NM_001352713.1
RefSeq - NM_001352714.1
RefSeq - NM_001352715.1
RefSeq - NM_001352716.1
RefSeq - NM_001352717.1
RefSeq - NM_001352718.1
RefSeq - NM_001352719.1
RefSeq - NM_001352720.1
RefSeq - NM_001352721.1
RefSeq - NM_001352722.1
RefSeq - NM_001352723.1
RefSeq - NM_001352724.1
RefSeq - NM_001352725.1
RefSeq - NM_001352726.1
RefSeq - NM_001352727.1
RefSeq - NM_001352728.1
RefSeq - NM_001352729.1
RefSeq - NM_001352730.1
RefSeq - NM_001352731.1
RefSeq - NM_001352732.1
RefSeq - NM_001352733.1
RefSeq - NM_001352734.1
RefSeq - NM_001352735.1
RefSeq - NM_001352736.1
RefSeq - NM_001352737.1
RefSeq - NM_001352738.1
RefSeq - NM_001352739.1
RefSeq - NM_001352740.1
RefSeq - NM_001352741.1
RefSeq - NM_001352742.1
RefSeq - NM_001352743.1
RefSeq - NM_001352744.1
RefSeq - NM_001352745.1
RefSeq - NM_001352746.1
RefSeq - NM_001352747.1
RefSeq - NM_001352748.1
RefSeq - NM_001352749.1
RefSeq - NM_001352750.1
RefSeq - NM_001352751.1
RefSeq - NM_001352752.1
RefSeq - NM_005607.4
RefSeq - NM_153831.3
RefSeq - XM_024447204.1
RefSeq - XM_024447205.1
RefSeq - XM_024447206.1
RefSeq - XM_024447207.1
RefSeq - XM_024447208.1
RefSeq - XM_024447209.1
RefSeq - XM_024447210.1
RefSeq - XM_024447211.1
RefSeq - XM_024447212.1
RefSeq - NR_148036.1
RefSeq - NR_148037.1
RefSeq - NR_148038.1
RefSeq - NR_148039.1
RefSeq - XM_017013653.2
RefSeq - XM_017013654.2
RefSeq - XM_017013656.2
RefSeq - XM_017013657.2
RefSeq - XM_017013664.2
RefSeq - XM_017013666.1
RefSeq - XM_017013669.2
RefSeq - XM_017013684.2
RefSeq - XM_017013688.2
RefSeq - XM_024447199.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000169398 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001890 placenta development TAS
 biological_processGO:0001932 regulation of protein phosphorylation IGI
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0003007 heart morphogenesis TAS
 biological_processGO:0007097 nuclear migration IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007172 signal complex assembly IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0007229 integrin-mediated signaling pathway TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0010507 negative regulation of autophagy IEA
 biological_processGO:0010594 regulation of endothelial cell migration TAS
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0010632 regulation of epithelial cell migration IGI
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0021955 central nervous system neuron axonogenesis IEA
 biological_processGO:0022408 negative regulation of cell-cell adhesion IDA
 biological_processGO:0030010 establishment of cell polarity TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030155 regulation of cell adhesion IBA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin IDA
 biological_processGO:0038007 netrin-activated signaling pathway TAS
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043087 regulation of GTPase activity TAS
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity TAS
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0045667 regulation of osteoblast differentiation IMP
 biological_processGO:0045860 positive regulation of protein kinase activity IMP
 biological_processGO:0046621 negative regulation of organ growth IEA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0048870 cell motility TAS
 biological_processGO:0050771 negative regulation of axonogenesis IEA
 biological_processGO:0051493 regulation of cytoskeleton organization TAS
 biological_processGO:0051893 regulation of focal adhesion assembly TAS
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0051964 negative regulation of synapse assembly IEA
 biological_processGO:0060396 growth hormone receptor signaling pathway IDA
 biological_processGO:1900024 regulation of substrate adhesion-dependent cell spreading IGI
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process ISS
 biological_processGO:2000811 negative regulation of anoikis IMP
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0043197 dendritic spine IBA
 molecular_functionGO:0003779 actin binding IDA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IDA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008432 JUN kinase binding IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042169 SH2 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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