5770


Homo sapiens (NCBI)

Features
Gene ID: 5770
  
Biological name :
  
Synonyms : protein tyrosine phosphatase, non-receptor type 1 / PTP1B / PTPN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202716_at (Human Genome U133 Plus 2.0 Array)   217686_at (Human Genome U133 Plus 2.0 Array)   217689_at (Human Genome U133 Plus 2.0 Array)   239526_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4506289
RefSeq - 519666804
RefSeq - NC_000020.11
RefSeq - NG_012119.1
RefSeq - NP_001265547.1
RefSeq - NP_002818.1
RefSeq - NM_001278618.1
RefSeq - NM_002827.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000196396 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IMP
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0009966 regulation of signal transduction IMP
 biological_processGO:0009968 negative regulation of signal transduction TAS
 biological_processGO:0030100 regulation of endocytosis IDA
 biological_processGO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway ISS
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IDA
 biological_processGO:0031532 actin cytoskeleton reorganization IMP
 biological_processGO:0033157 regulation of intracellular protein transport IMP
 biological_processGO:0034620 cellular response to unfolded protein TAS
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IMP
 biological_processGO:0035791 platelet-derived growth factor receptor-beta signaling pathway IMP
 biological_processGO:0036498 IRE1-mediated unfolded protein response IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IMP
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway NAS
 biological_processGO:0060338 regulation of type I interferon-mediated signaling pathway TAS
 biological_processGO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway TAS
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IDA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:1902202 regulation of hepatocyte growth factor receptor signaling pathway IMP
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903896 positive regulation of IRE1-mediated unfolded protein response TAS
 biological_processGO:1903898 negative regulation of PERK-mediated unfolded protein response IDA
 biological_processGO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity ISS
 biological_processGO:2000646 positive regulation of receptor catabolic process IMP
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0097443 sorting endosome ISS
 cellular_componentGO:0098554 cytoplasmic side of endoplasmic reticulum membrane IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005158 insulin receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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