5771


Homo sapiens (NCBI)

Features
Gene ID: 5771
  
Biological name :
  
Synonyms : protein tyrosine phosphatase, non-receptor type 2 / PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP / PTPN2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204935_at (Human Genome U133 Plus 2.0 Array)   213136_at (Human Genome U133 Plus 2.0 Array)   213137_s_at (Human Genome U133 Plus 2.0 Array)   241622_at (Human Genome U133 Plus 2.0 Array)   241623_at (Human Genome U133 Plus 2.0 Array)   241983_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767997800
RefSeq - 1034604441
RefSeq - 1034604444
RefSeq - 1034604446
RefSeq - 1034604448
RefSeq - 1370473690
RefSeq - 1370473692
RefSeq - 1370473694
RefSeq - 18104980
RefSeq - 18104982
RefSeq - 333108231
RefSeq - 333108235
RefSeq - 530424900
RefSeq - 530424902
RefSeq - 1034604439
RefSeq - 767997803
RefSeq - 767997805
RefSeq - 815891366
RefSeq - NC_000018.10
RefSeq - NG_029116.1
RefSeq - NP_001193942.1
RefSeq - NP_001295216.1
RefSeq - NP_002819.2
RefSeq - NP_536347.1
RefSeq - NP_536348.1
RefSeq - XP_005258181.1
RefSeq - XP_005258182.1
RefSeq - XP_011524007.1
RefSeq - XP_011524008.1
RefSeq - XP_011524009.1
RefSeq - XP_016881373.1
RefSeq - XP_016881374.1
RefSeq - XP_016881375.1
RefSeq - XP_016881376.1
RefSeq - XP_016881377.1
RefSeq - XP_024306996.1
RefSeq - XP_024306997.1
RefSeq - XP_024306998.1
RefSeq - NM_001207013.1
RefSeq - NM_001308287.1
RefSeq - NM_002828.3
RefSeq - NM_080422.2
RefSeq - NM_080423.2
RefSeq - XM_017025887.2
RefSeq - XM_017025888.2
RefSeq - XM_024451228.1
RefSeq - XM_024451229.1
RefSeq - XM_024451230.1
RefSeq - XM_005258124.4
RefSeq - XM_005258125.4
RefSeq - XM_011525705.3
RefSeq - XM_011525706.2
RefSeq - XM_011525707.2
RefSeq - XM_017025884.1
RefSeq - XM_017025885.2
RefSeq - XM_017025886.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000175354 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008286 insulin receptor signaling pathway ISS
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway ISS
 biological_processGO:0010888 negative regulation of lipid storage ISS
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0030217 T cell differentiation ISS
 biological_processGO:0030218 erythrocyte differentiation ISS
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IMP
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IMP
 biological_processGO:0042532 negative regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0045650 negative regulation of macrophage differentiation ISS
 biological_processGO:0045722 positive regulation of gluconeogenesis ISS
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway ISS
 biological_processGO:0050728 negative regulation of inflammatory response ISS
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway ISS
 biological_processGO:0050922 negative regulation of chemotaxis ISS
 biological_processGO:0060334 regulation of interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060336 negative regulation of interferon-gamma-mediated signaling pathway ISS
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IMP
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070104 negative regulation of interleukin-6-mediated signaling pathway IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:1902202 regulation of hepatocyte growth factor receptor signaling pathway IMP
 biological_processGO:1902206 negative regulation of interleukin-2-mediated signaling pathway IMP
 biological_processGO:1902215 negative regulation of interleukin-4-mediated signaling pathway IEA
 biological_processGO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway ISS
 biological_processGO:1902233 negative regulation of positive thymic T cell selection ISS
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903899 positive regulation of PERK-mediated unfolded protein response IEA
 biological_processGO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0004726 non-membrane spanning protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019905 syntaxin binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0097677 STAT family protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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