5777


Homo sapiens (NCBI)

Features
Gene ID: 5777
  
Biological name :
  
Synonyms : HCP|HCPH|HPTP1C|PTP-1C|SH-PTP1|SHP-1|SHP-1L|SHP1 / protein tyrosine phosphatase, non-receptor type 6 / PTPN6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206687_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1370462512
RefSeq - 18104989
RefSeq - 18104991
RefSeq - 18104993
RefSeq - 578822640
RefSeq - 767971404
RefSeq - NC_000012.12
RefSeq - NP_002822.2
RefSeq - NP_536858.1
RefSeq - NP_536859.1
RefSeq - XP_006719057.1
RefSeq - XP_011519290.1
RefSeq - XP_024304874.1
RefSeq - NM_002831.5
RefSeq - NM_080548.4
RefSeq - NM_080549.3
RefSeq - XM_006718994.1
RefSeq - XM_011520988.2
RefSeq - XM_024449106.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000111679 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin IEA
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030154 cell differentiation IDA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030220 platelet formation IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0033277 abortive mitotic cell cycle IEA
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0035855 megakaryocyte development IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0045577 regulation of B cell differentiation IEA
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050853 B cell receptor signaling pathway IEA
 biological_processGO:0050859 negative regulation of B cell receptor signaling pathway IEA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051279 regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0060338 regulation of type I interferon-mediated signaling pathway TAS
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0070527 platelet aggregation IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0042105 alpha-beta T cell receptor complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904724 tertiary granule lumen TAS
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042169 SH2 domain binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IEA
 molecular_functionGO:0140031 phosphorylation-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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