5925


Homo sapiens (NCBI)

Features
Gene ID: 5925
  
Biological name :
  
Synonyms : OSRC|PPP1R130|RB|p105-Rb|pRb|pp110 / RB1 / RB transcriptional corepressor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203132_at (Human Genome U133 Plus 2.0 Array)   211540_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 108773787
RefSeq - 767977928
RefSeq - NC_000013.11
RefSeq - NG_009009.1
RefSeq - NP_000312.2
RefSeq - XP_011533473.1
RefSeq - NM_000321.2
RefSeq - XM_011535171.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000139687 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0001894 tissue homeostasis IEA
 biological_processGO:0003180 aortic valve morphogenesis ISS
 biological_processGO:0006338 chromatin remodeling TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006469 negative regulation of protein kinase activity IPI
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0007093 mitotic cell cycle checkpoint TAS
 biological_processGO:0007265 Ras protein signal transduction IEP
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0031134 sister chromatid biorientation IMP
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0034088 maintenance of mitotic sister chromatid cohesion IMP
 biological_processGO:0034349 glial cell apoptotic process IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0042551 neuron maturation IEA
 biological_processGO:0043353 enucleate erythrocyte differentiation IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity TAS
 biological_processGO:0043550 regulation of lipid kinase activity IDA
 biological_processGO:0045445 myoblast differentiation IMP
 biological_processGO:0045651 positive regulation of macrophage differentiation IEA
 biological_processGO:0045842 positive regulation of mitotic metaphase/anaphase transition IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0048667 cell morphogenesis involved in neuron differentiation IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050728 negative regulation of inflammatory response ISS
 biological_processGO:0051146 striated muscle cell differentiation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0071459 protein localization to chromosome, centromeric region IMP
 biological_processGO:0071466 cellular response to xenobiotic stimulus IEA
 biological_processGO:0071922 regulation of cohesin loading IMP
 biological_processGO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle TAS
 biological_processGO:0090230 regulation of centromere complex assembly TAS
 biological_processGO:0097284 hepatocyte apoptotic process IEA
 biological_processGO:1903055 positive regulation of extracellular matrix organization ISS
 biological_processGO:1904028 positive regulation of collagen fibril organization ISS
 biological_processGO:1904761 negative regulation of myofibroblast differentiation ISS
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle TAS
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IDA
 cellular_componentGO:0000785 chromatin TAS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0008024 cyclin/CDK positive transcription elongation factor complex IDA
 cellular_componentGO:0016514 SWI/SNF complex TAS
 cellular_componentGO:0016605 PML body IDA
 cellular_componentGO:0035189 Rb-E2F complex TAS
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001012 RNA polymerase II regulatory region DNA binding IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0019900 kinase binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0050681 androgen receptor binding NAS
 molecular_functionGO:0051219 phosphoprotein binding IPI
 molecular_functionGO:0061676 importin-alpha family protein binding IPI
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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