6262


Homo sapiens (NCBI)

Features
Gene ID: 6262
  
Biological name :
  
Synonyms : ARVC2|ARVD2|RYR-2|RyR|VTSIP / ryanodine receptor 2 / RYR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207557_s_at (Human Genome U133 Plus 2.0 Array)   214044_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000001.11
RefSeq - XP_006711865.1
RefSeq - XP_006711866.1
RefSeq - XP_006711867.1
RefSeq - XP_006711868.1
RefSeq - XP_006711869.1
RefSeq - XP_006711870.1
RefSeq - XP_006711871.1
RefSeq - XP_006711873.1
RefSeq - XP_016857517.1
RefSeq - NG_008799.2
RefSeq - 1034560884
RefSeq - 112799847
RefSeq - NP_001026.2
RefSeq - 578802297
RefSeq - 578802299
RefSeq - 578802301
RefSeq - 578802303
RefSeq - 578802305
RefSeq - 578802307
RefSeq - 578802309
RefSeq - 578802313
RefSeq - XR_949152.2
RefSeq - NM_001035.2
RefSeq - XM_006711802.3
RefSeq - XM_006711803.3
RefSeq - XM_006711804.3
RefSeq - XM_006711805.3
RefSeq - XM_006711806.3
RefSeq - XM_006711807.3
RefSeq - XM_006711808.3
RefSeq - XM_006711810.3
RefSeq - XM_017002028.1
RefSeq - XR_002957299.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198626 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia ISS
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0003143 embryonic heart tube morphogenesis ISS
 biological_processGO:0003220 left ventricular cardiac muscle tissue morphogenesis ISS
 biological_processGO:0003300 cardiac muscle hypertrophy ISS
 biological_processGO:0005513 detection of calcium ion IDA
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006874 cellular calcium ion homeostasis ISS
 biological_processGO:0010460 positive regulation of heart rate ISS
 biological_processGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion ISS
 biological_processGO:0010882 regulation of cardiac muscle contraction by calcium ion signaling IMP
 biological_processGO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISS
 biological_processGO:0014850 response to muscle activity IMP
 biological_processGO:0019722 calcium-mediated signaling ISS
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0031000 response to caffeine IDA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IDA
 biological_processGO:0035994 response to muscle stretch IMP
 biological_processGO:0051209 release of sequestered calcium ion into cytosol ISS
 biological_processGO:0051284 positive regulation of sequestering of calcium ion IDA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration ISS
 biological_processGO:0051775 response to redox state IDA
 biological_processGO:0055117 regulation of cardiac muscle contraction IMP
 biological_processGO:0060048 cardiac muscle contraction IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060402 calcium ion transport into cytosol IDA
 biological_processGO:0070296 sarcoplasmic reticulum calcium ion transport TAS
 biological_processGO:0071313 cellular response to caffeine ISS
 biological_processGO:0071872 cellular response to epinephrine stimulus TAS
 biological_processGO:0072599 establishment of protein localization to endoplasmic reticulum IDA
 biological_processGO:0086005 ventricular cardiac muscle cell action potential ISS
 biological_processGO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling ISS
 biological_processGO:0086064 cell communication by electrical coupling involved in cardiac conduction IC
 biological_processGO:0097050 type B pancreatic cell apoptotic process IMP
 biological_processGO:0098735 positive regulation of the force of heart contraction IMP
 biological_processGO:0098904 regulation of AV node cell action potential IMP
 biological_processGO:0098907 regulation of SA node cell action potential IMP
 biological_processGO:0098910 regulation of atrial cardiac muscle cell action potential IMP
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential IMP
 biological_processGO:1901896 positive regulation of calcium-transporting ATPase activity IDA
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0014701 junctional sarcoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 cellular_componentGO:0030018 Z disc ISS
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0033017 sarcoplasmic reticulum membrane TAS
 cellular_componentGO:0034704 calcium channel complex IDA
 cellular_componentGO:0042383 sarcolemma IBA
 molecular_functionGO:0005219 ryanodine-sensitive calcium-release channel activity TAS
 molecular_functionGO:0005262 calcium channel activity ISS
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding ISS
 molecular_functionGO:0015278 calcium-release channel activity ISS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IDA
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0043924 suramin binding IMP
 molecular_functionGO:0044325 ion channel binding ISS
 molecular_functionGO:0048763 calcium-induced calcium release activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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