6347


Homo sapiens (NCBI)

Features
Gene ID: 6347
  
Biological name :
  
Synonyms : CCL2 / C-C motif chemokine ligand 2 / GDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 216598_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4506841
RefSeq - NC_000017.11
RefSeq - NG_012123.1
RefSeq - NP_002973.1
RefSeq - NM_002982.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000108691 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IMP
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0002548 monocyte chemotaxis IDA
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IDA
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0007010 cytoskeleton organization IDA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007259 JAK-STAT cascade TAS
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0009617 response to bacterium NAS
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019079 viral genome replication TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019725 cellular homeostasis TAS
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0034351 negative regulation of glial cell apoptotic process IDA
 biological_processGO:0035684 helper T cell extravasation ISS
 biological_processGO:0036499 PERK-mediated unfolded protein response TAS
 biological_processGO:0043491 protein kinase B signaling IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0043615 astrocyte cell migration IDA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEP
 biological_processGO:0048245 eosinophil chemotaxis IBA
 biological_processGO:0048246 macrophage chemotaxis IDA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050870 positive regulation of T cell activation ISS
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process ISS
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide ISS
 biological_processGO:0071346 cellular response to interferon-gamma ISS
 biological_processGO:0071347 cellular response to interleukin-1 ISS
 biological_processGO:0071356 cellular response to tumor necrosis factor ISS
 biological_processGO:0071407 cellular response to organic cyclic compound IDA
 biological_processGO:0090280 positive regulation of calcium ion import IDA
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation IMP
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IMP
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process IMP
 biological_processGO:2000427 positive regulation of apoptotic cell clearance ISS
 biological_processGO:2000502 negative regulation of natural killer cell chemotaxis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0031727 CCR2 chemokine receptor binding TAS
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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