6352


Homo sapiens (NCBI)

Features
Gene ID: 6352
  
Biological name :
  
Synonyms : CCL5 / C-C motif chemokine ligand 5 / D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1405_i_at (Human Genome U133 Plus 2.0 Array)   1555759_a_at (Human Genome U133 Plus 2.0 Array)   204655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 22538814
RefSeq - 524563423
RefSeq - NC_000017.11
RefSeq - NG_015990.1
RefSeq - NP_002976.2
RefSeq - NT_187614.1
RefSeq - NP_001265665.1
RefSeq - NM_001278736.1
RefSeq - NM_002985.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000271503 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IMP
 biological_processGO:0002407 dendritic cell chemotaxis TAS
 biological_processGO:0002548 monocyte chemotaxis IC
 biological_processGO:0002676 regulation of chronic inflammatory response TAS
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006874 cellular calcium ion homeostasis IDA
 biological_processGO:0006887 exocytosis IDA
 biological_processGO:0006935 chemotaxis NAS
 biological_processGO:0006954 inflammatory response IDA
 biological_processGO:0007159 leukocyte cell-cell adhesion IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling IDA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity TAS
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IDA
 biological_processGO:0010820 positive regulation of T cell chemotaxis IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0031328 positive regulation of cellular biosynthetic process IDA
 biological_processGO:0031584 activation of phospholipase D activity IDA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0033634 positive regulation of cell-cell adhesion mediated by integrin IDA
 biological_processGO:0034112 positive regulation of homotypic cell-cell adhesion IDA
 biological_processGO:0042102 positive regulation of T cell proliferation IDA
 biological_processGO:0042119 neutrophil activation IDA
 biological_processGO:0042327 positive regulation of phosphorylation IDA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0043491 protein kinase B signaling IMP
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0043922 negative regulation by host of viral transcription IDA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEP
 biological_processGO:0045070 positive regulation of viral genome replication TAS
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045089 positive regulation of innate immune response TAS
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 biological_processGO:0045948 positive regulation of translational initiation NAS
 biological_processGO:0046427 positive regulation of JAK-STAT cascade TAS
 biological_processGO:0048245 eosinophil chemotaxis IDA
 biological_processGO:0048246 macrophage chemotaxis TAS
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0050796 regulation of insulin secretion IDA
 biological_processGO:0050863 regulation of T cell activation IDA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0051262 protein tetramerization IDA
 biological_processGO:0051928 positive regulation of calcium ion transport IDA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway TAS
 biological_processGO:0070100 negative regulation of chemokine-mediated signaling pathway IEA
 biological_processGO:0070233 negative regulation of T cell apoptotic process IDA
 biological_processGO:0070234 positive regulation of T cell apoptotic process IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IEP
 biological_processGO:0071347 cellular response to interleukin-1 IEP
 biological_processGO:0071356 cellular response to tumor necrosis factor IEP
 biological_processGO:0071407 cellular response to organic cyclic compound IDA
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IDA
 biological_processGO:1901214 regulation of neuron death IDA
 biological_processGO:2000110 negative regulation of macrophage apoptotic process IEA
 biological_processGO:2000406 positive regulation of T cell migration IDA
 biological_processGO:2000503 positive regulation of natural killer cell chemotaxis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity NAS
 molecular_functionGO:0016004 phospholipase activator activity IDA
 molecular_functionGO:0030298 receptor signaling protein tyrosine kinase activator activity IDA
 molecular_functionGO:0031726 CCR1 chemokine receptor binding TAS
 molecular_functionGO:0031729 CCR4 chemokine receptor binding TAS
 molecular_functionGO:0031730 CCR5 chemokine receptor binding IPI
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0042379 chemokine receptor binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043621 protein self-association IDA
 molecular_functionGO:0046817 chemokine receptor antagonist activity IDA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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