6376


Homo sapiens (NCBI)

Features
Gene ID: 6376
  
Biological name :
  
Synonyms : ABCD-3|C3Xkine|CXC3|CXC3C|NTN|NTT|SCYD1|fractalkine|neurotactin / CX3CL1 / C-X3-C motif chemokine ligand 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203687_at (Human Genome U133 Plus 2.0 Array)   823_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001291321.1
RefSeq - NP_002987.1
RefSeq - NC_000016.10
RefSeq - 4506857
RefSeq - 749385058
RefSeq - NM_001304392.2
RefSeq - NM_002996.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000006210 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002523 leukocyte migration involved in inflammatory response IMP
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IMP
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0030595 leukocyte chemotaxis TAS
 biological_processGO:0032914 positive regulation of transforming growth factor beta1 production IEA
 biological_processGO:0033622 integrin activation IMP
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0048245 eosinophil chemotaxis IBA
 biological_processGO:0048246 macrophage chemotaxis IEA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050729 positive regulation of inflammatory response IEP
 biological_processGO:0050902 leukocyte adhesive activation TAS
 biological_processGO:0051041 positive regulation of calcium-independent cell-cell adhesion IDA
 biological_processGO:0060055 angiogenesis involved in wound healing IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005178 integrin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0031737 CX3C chemokine receptor binding IDA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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