641


Homo sapiens (NCBI)

Features
Gene ID: 641
  
Biological name :
  
Synonyms : BLM / Bloom syndrome RecQ like helicase / BS|RECQ2|RECQL2|RECQL3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205733_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4557365
RefSeq - 564730687
RefSeq - 564730689
RefSeq - 564730691
RefSeq - 578827270
RefSeq - 767984938
RefSeq - 767984940
RefSeq - NC_000015.10
RefSeq - NG_007272.1
RefSeq - NP_000048.1
RefSeq - NP_001274175.1
RefSeq - NP_001274176.1
RefSeq - NP_001274177.1
RefSeq - XP_006720695.1
RefSeq - XP_011520183.1
RefSeq - XP_011520184.1
RefSeq - NM_000057.3
RefSeq - NM_001287246.1
RefSeq - NM_001287247.1
RefSeq - NM_001287248.1
RefSeq - XM_011521882.3
RefSeq - XM_006720632.2
RefSeq - XM_011521881.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000197299 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IMP
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0000724 double-strand break repair via homologous recombination NAS
 biological_processGO:0000729 DNA double-strand break processing IDA
 biological_processGO:0000731 DNA synthesis involved in DNA repair IBA
 biological_processGO:0000732 strand displacement IBA
 biological_processGO:0000733 DNA strand renaturation IEA
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006281 DNA repair NAS
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IBA
 biological_processGO:0006310 DNA recombination NAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IDA
 biological_processGO:0010165 response to X-ray IDA
 biological_processGO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination IBA
 biological_processGO:0031297 replication fork processing IDA
 biological_processGO:0032508 DNA duplex unwinding IDA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0044806 G-quadruplex DNA unwinding ISS
 biological_processGO:0045003 double-strand break repair via synthesis-dependent strand annealing IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045910 negative regulation of DNA recombination IMP
 biological_processGO:0045950 negative regulation of mitotic recombination IBA
 biological_processGO:0046632 alpha-beta T cell differentiation IBA
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation IBA
 biological_processGO:0048478 replication fork protection NAS
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:0051307 meiotic chromosome separation IBA
 biological_processGO:0051782 negative regulation of cell division IMP
 biological_processGO:0061820 telomeric D-loop disassembly IDA
 biological_processGO:0070244 negative regulation of thymocyte apoptotic process IBA
 biological_processGO:0071139 resolution of recombination intermediates IBA
 biological_processGO:0071479 cellular response to ionizing radiation IDA
 biological_processGO:0072711 cellular response to hydroxyurea IDA
 biological_processGO:0072757 cellular response to camptothecin IDA
 biological_processGO:0090329 regulation of DNA-dependent DNA replication IMP
 biological_processGO:0090656 t-circle formation TAS
 biological_processGO:1901291 negative regulation of double-strand break repair via single-strand annealing IBA
 biological_processGO:1905168 positive regulation of double-strand break repair via homologous recombination IBA
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0000781 chromosome, telomeric region IDA
 cellular_componentGO:0000800 lateral element IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005657 replication fork ISS
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016363 nuclear matrix IDA
 cellular_componentGO:0016605 PML body IDA
 cellular_componentGO:0045120 pronucleus IBA
 molecular_functionGO:0000400 four-way junction DNA binding IDA
 molecular_functionGO:0000403 Y-form DNA binding IDA
 molecular_functionGO:0000405 bubble DNA binding IDA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003678 DNA helicase activity IDA
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IMP
 molecular_functionGO:0004386 helicase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008026 ATP-dependent helicase activity IDA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IDA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0009378 four-way junction helicase activity IDA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0036310 annealing helicase activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043140 ATP-dependent 3"-5" DNA helicase activity IBA
 molecular_functionGO:0051880 G-quadruplex DNA binding IDA
 molecular_functionGO:0061749 forked DNA-dependent helicase activity IDA
 molecular_functionGO:0061821 telomeric D-loop binding IDA
 molecular_functionGO:0061849 telomeric G-quadruplex DNA binding IC
 molecular_functionGO:1905773 8-hydroxy-2"-deoxyguanosine DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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