6416


Homo sapiens (NCBI)

Features
Gene ID: 6416
  
Biological name :
  
Synonyms : JNKK|JNKK1|MAPKK4|MEK4|MKK4|PRKMK4|SAPKK-1|SAPKK1|SEK1|SERK1|SKK1 / MAP2K4 / mitogen-activated protein kinase kinase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203265_s_at (Human Genome U133 Plus 2.0 Array)   203266_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4506889
RefSeq - 526479851
RefSeq - 530410551
RefSeq - 530410555
RefSeq - 767992456
RefSeq - 767992458
RefSeq - NC_000017.11
RefSeq - NG_033952.1
RefSeq - NP_001268364.1
RefSeq - NP_003001.1
RefSeq - XP_005256810.1
RefSeq - XP_005256812.1
RefSeq - XP_011522278.1
RefSeq - XP_011522279.1
RefSeq - XM_011523976.2
RefSeq - XM_011523977.2
RefSeq - NM_001281435.1
RefSeq - NM_003010.3
RefSeq - XR_001752584.2
RefSeq - XR_934080.2
RefSeq - XM_005256753.3
RefSeq - XM_005256755.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000065559 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0034393 positive regulation of smooth muscle cell apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IEA
 biological_processGO:0061049 cell growth involved in cardiac muscle cell development IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0072709 cellular response to sorbitol IEA
 biological_processGO:2000672 negative regulation of motor neuron apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0032839 dendrite cytoplasm IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004708 MAP kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008545 JUN kinase kinase activity IEA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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