64383


Mus musculus (NCBI)

Features
Gene ID: 64383
  
Biological name :
  
Synonyms : 5730427M03Rik|SIR2L2|Sir2l / Sirt2 / sirtuin 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423507_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017167706.1
RefSeq - 1039779587
RefSeq - 1039779589
RefSeq - 1039779591
RefSeq - 170650630
RefSeq - 170650632
RefSeq - 170650634
RefSeq - NC_000073.6
RefSeq - NP_001116237.1
RefSeq - NP_001116238.1
RefSeq - NP_071877.3
RefSeq - XP_017167703.1
RefSeq - XP_017167704.1
RefSeq - XP_017167705.1
RefSeq - 1039779585
RefSeq - NM_001122765.1
RefSeq - NM_001122766.1
RefSeq - NM_022432.4
RefSeq - XM_017312215.1
RefSeq - XM_017312216.1
RefSeq - XM_017312217.1
RefSeq - XM_017312214.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000015149 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006476 protein deacetylation ISO
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0010507 negative regulation of autophagy ISO
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation IMP
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016575 histone deacetylation IGI
 biological_processGO:0022011 myelination in peripheral nervous system ISO
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031641 regulation of myelination ISO
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0034599 cellular response to oxidative stress IDA
 biological_processGO:0034983 peptidyl-lysine deacetylation ISO
 biological_processGO:0035729 cellular response to hepatocyte growth factor stimulus ISO
 biological_processGO:0042177 negative regulation of protein catabolic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0044242 cellular lipid catabolic process IMP
 biological_processGO:0045598 regulation of fat cell differentiation IMP
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0045836 positive regulation of meiotic nuclear division IMP
 biological_processGO:0045843 negative regulation of striated muscle tissue development ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048012 hepatocyte growth factor receptor signaling pathway ISO
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation ISO
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0051726 regulation of cell cycle ISO
 biological_processGO:0051781 positive regulation of cell division IMP
 biological_processGO:0051987 positive regulation of attachment of spindle microtubules to kinetochore IMP
 biological_processGO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
 biological_processGO:0061433 cellular response to caloric restriction IDA
 biological_processGO:0070446 negative regulation of oligodendrocyte progenitor proliferation ISO
 biological_processGO:0070932 histone H3 deacetylation ISO
 biological_processGO:0070933 histone H4 deacetylation ISO
 biological_processGO:0071219 cellular response to molecule of bacterial origin ISO
 biological_processGO:0071456 cellular response to hypoxia ISO
 biological_processGO:0071872 cellular response to epinephrine stimulus IDA
 biological_processGO:0090042 tubulin deacetylation ISO
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IMP
 biological_processGO:1900195 positive regulation of oocyte maturation IMP
 biological_processGO:1900226 negative regulation of NLRP3 inflammasome complex assembly IMP
 biological_processGO:1900425 negative regulation of defense response to bacterium ISO
 biological_processGO:1901026 ripoptosome assembly involved in necroptotic process IMP
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome ISO
 cellular_componentGO:0005720 nuclear heterochromatin ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005814 centriole ISO
 cellular_componentGO:0005819 spindle ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0033010 paranodal junction ISO
 cellular_componentGO:0033270 paranode region of axon ISO
 cellular_componentGO:0035748 myelin sheath abaxonal region ISO
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0043209 myelin sheath ISO
 cellular_componentGO:0043219 lateral loop ISO
 cellular_componentGO:0043220 Schmidt-Lanterman incisure ISO
 cellular_componentGO:0044224 juxtaparanode region of axon ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0072686 mitotic spindle ISO
 cellular_componentGO:0072687 meiotic spindle IDA
 cellular_componentGO:0097386 glial cell projection ISO
 cellular_componentGO:0097456 terminal loop ISO
 molecular_functionGO:0003682 chromatin binding ISO
 molecular_functionGO:0004407 histone deacetylase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017136 NAD-dependent histone deacetylase activity ISO
 molecular_functionGO:0033558 protein deacetylase activity ISO
 molecular_functionGO:0034979 NAD-dependent protein deacetylase activity ISO
 molecular_functionGO:0035035 histone acetyltransferase binding ISO
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0042903 tubulin deacetylase activity ISO
 molecular_functionGO:0043130 ubiquitin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) ISO
 molecular_functionGO:0048487 beta-tubulin binding IDA
 molecular_functionGO:0070403 NAD+ binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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