Manteia

6469

Homo sapiens (NCBI)

Features

Gene ID:	6469

Biological name :

Synonyms :	HHG1\|HLP3\|HPE3\|MCOPCB5\|SMMCI\|ShhNC\|TPT\|TPTPS / SHH / sonic hedgehog

Possible biological names infered from orthology :

Species:	Homo sapiens (NCBI)

Chr. number:
Strand:
Band:
Gene start:
Gene end:

Corresponding Affymetrix probe sets:	207586_at (Human Genome U133 Plus 2.0 Array) 236263_at (Human Genome U133 Plus 2.0 Array)

Cross references:	RefSeq - XP_011514782.1 RefSeq - 767948481 RefSeq - 767948483 RefSeq - 881717124 RefSeq - NC_000007.14 RefSeq - NG_007504.2 RefSeq - NP_000184.1 RefSeq - NP_001297391.1 RefSeq - XP_011514781.1 RefSeq - 4506939 RefSeq - NR_132318.1 RefSeq - NR_132319.1 RefSeq - NM_000193.3 RefSeq - NM_001310462.1 RefSeq - XM_011516479.2 RefSeq - XM_011516480.2

See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164690 to get all the annotations available for this gene.

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISS
biological_process	GO:0001569	branching involved in blood vessel morphogenesis	ISS
biological_process	GO:0001570	vasculogenesis	ISS
biological_process	GO:0001656	metanephros development	ISS
biological_process	GO:0001658	branching involved in ureteric bud morphogenesis	ISS
biological_process	GO:0001708	cell fate specification	ISS
biological_process	GO:0001755	neural crest cell migration	ISS
biological_process	GO:0001947	heart looping	ISS
biological_process	GO:0002052	positive regulation of neuroblast proliferation	IEA
biological_process	GO:0002076	osteoblast development	IEA
biological_process	GO:0002320	lymphoid progenitor cell differentiation	IMP
biological_process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	ISS
biological_process	GO:0006897	endocytosis	IEA
biological_process	GO:0007224	smoothened signaling pathway	ISS
biological_process	GO:0007228	positive regulation of hh target transcription factor activity	ISS
biological_process	GO:0007267	cell-cell signaling	ISS
biological_process	GO:0007389	pattern specification process	ISS
biological_process	GO:0007398	ectoderm development	IEA
biological_process	GO:0007405	neuroblast proliferation	ISS
biological_process	GO:0007411	axon guidance	ISS
biological_process	GO:0007417	central nervous system development	ISS
biological_process	GO:0007418	ventral midline development	TAS
biological_process	GO:0007442	hindgut morphogenesis	IEA
biological_process	GO:0007507	heart development	ISS
biological_process	GO:0007596	blood coagulation	IEA
biological_process	GO:0008209	androgen metabolic process	ISS
biological_process	GO:0008284	positive regulation of cell proliferation	ISS
biological_process	GO:0009880	embryonic pattern specification	TAS
biological_process	GO:0009949	polarity specification of anterior/posterior axis	ISS
biological_process	GO:0009953	dorsal/ventral pattern formation	ISS
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0014003	oligodendrocyte development	IEA
biological_process	GO:0014706	striated muscle tissue development	IEA
biological_process	GO:0014858	positive regulation of skeletal muscle cell proliferation	IEA
biological_process	GO:0014902	myotube differentiation	IEA
biological_process	GO:0016539	intein-mediated protein splicing	IEA
biological_process	GO:0021513	spinal cord dorsal/ventral patterning	IEA
biological_process	GO:0021522	spinal cord motor neuron differentiation	IEA
biological_process	GO:0021794	thalamus development	IEA
biological_process	GO:0021904	dorsal/ventral neural tube patterning	IEA
biological_process	GO:0021930	cerebellar granule cell precursor proliferation	ISS
biological_process	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	IEA
biological_process	GO:0021978	telencephalon regionalization	IEA
biological_process	GO:0030010	establishment of cell polarity	IEA
biological_process	GO:0030162	regulation of proteolysis	ISS
biological_process	GO:0030177	positive regulation of Wnt signaling pathway	IEA
biological_process	GO:0030324	lung development	ISS
biological_process	GO:0030326	embryonic limb morphogenesis	ISS
biological_process	GO:0030336	negative regulation of cell migration	ISS
biological_process	GO:0030539	male genitalia development	ISS
biological_process	GO:0030850	prostate gland development	ISS
biological_process	GO:0030878	thyroid gland development	IEA
biological_process	GO:0030900	forebrain development	ISS
biological_process	GO:0030901	midbrain development	ISS
biological_process	GO:0030902	hindbrain development	ISS
biological_process	GO:0031016	pancreas development	IEA
biological_process	GO:0031069	hair follicle morphogenesis	IEA
biological_process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IEA
biological_process	GO:0033077	T cell differentiation in thymus	ISS
biological_process	GO:0033089	positive regulation of T cell differentiation in thymus	ISS
biological_process	GO:0033092	positive regulation of immature T cell proliferation in thymus	ISS
biological_process	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	IEA
biological_process	GO:0034504	protein localization to nucleus	IEA
biological_process	GO:0035115	embryonic forelimb morphogenesis	IEA
biological_process	GO:0035116	embryonic hindlimb morphogenesis	IEA
biological_process	GO:0042127	regulation of cell proliferation	ISS
biological_process	GO:0042130	negative regulation of T cell proliferation	IEA
biological_process	GO:0042307	positive regulation of protein import into nucleus	IEA
biological_process	GO:0042475	odontogenesis of dentin-containing tooth	IEA
biological_process	GO:0042481	regulation of odontogenesis	ISS
biological_process	GO:0042733	embryonic digit morphogenesis	ISS
biological_process	GO:0043010	camera-type eye development	IEA
biological_process	GO:0043066	negative regulation of apoptotic process	ISS
biological_process	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	IDA
biological_process	GO:0045059	positive thymic T cell selection	ISS
biological_process	GO:0045060	negative thymic T cell selection	ISS
biological_process	GO:0045109	intermediate filament organization	IEA
biological_process	GO:0045445	myoblast differentiation	IEA
biological_process	GO:0045596	negative regulation of cell differentiation	ISS
biological_process	GO:0045880	positive regulation of smoothened signaling pathway	ISS
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IDA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISS
biological_process	GO:0046638	positive regulation of alpha-beta T cell differentiation	ISS
biological_process	GO:0046639	negative regulation of alpha-beta T cell differentiation	IEA
biological_process	GO:0048468	cell development	ISS
biological_process	GO:0048538	thymus development	ISS
biological_process	GO:0048557	embryonic digestive tract morphogenesis	IEA
biological_process	GO:0048617	embryonic foregut morphogenesis	IEA
biological_process	GO:0048643	positive regulation of skeletal muscle tissue development	IEA
biological_process	GO:0048645	animal organ formation	IEA
biological_process	GO:0048663	neuron fate commitment	ISS
biological_process	GO:0048706	embryonic skeletal system development	IEA
biological_process	GO:0048714	positive regulation of oligodendrocyte differentiation	IEA
biological_process	GO:0048754	branching morphogenesis of an epithelial tube	ISS
biological_process	GO:0048839	inner ear development	IEA
biological_process	GO:0048859	formation of anatomical boundary	IEA
biological_process	GO:0048864	stem cell development	ISS
biological_process	GO:0051155	positive regulation of striated muscle cell differentiation	IEA
biological_process	GO:0051781	positive regulation of cell division	IDA
biological_process	GO:0060020	Bergmann glial cell differentiation	IEA
biological_process	GO:0060021	roof of mouth development	IEA
biological_process	GO:0060070	canonical Wnt signaling pathway	IEA
biological_process	GO:0060174	limb bud formation	IEA
biological_process	GO:0060428	lung epithelium development	IEA
biological_process	GO:0060439	trachea morphogenesis	IEA
biological_process	GO:0060445	branching involved in salivary gland morphogenesis	IEA
biological_process	GO:0060447	bud outgrowth involved in lung branching	IEA
biological_process	GO:0060458	right lung development	IEA
biological_process	GO:0060459	left lung development	IEA
biological_process	GO:0060463	lung lobe morphogenesis	IEA
biological_process	GO:0060484	lung-associated mesenchyme development	IEA
biological_process	GO:0060516	primary prostatic bud elongation	IEA
biological_process	GO:0060523	prostate epithelial cord elongation	IEA
biological_process	GO:0060662	salivary gland cavitation	IEA
biological_process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	IEA
biological_process	GO:0060685	regulation of prostatic bud formation	IEA
biological_process	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	IDA
biological_process	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	IEA
biological_process	GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	IEA
biological_process	GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	IEA
biological_process	GO:0060840	artery development	IEA
biological_process	GO:0060916	mesenchymal cell proliferation involved in lung development	IEA
biological_process	GO:0061053	somite development	ISS
biological_process	GO:0061189	positive regulation of sclerotome development	IDA
biological_process	GO:0071285	cellular response to lithium ion	IEA
biological_process	GO:0071542	dopaminergic neuron differentiation	TAS
biological_process	GO:0072001	renal system development	IEP
biological_process	GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	ISS
biological_process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IEA
biological_process	GO:0090370	negative regulation of cholesterol efflux	ISS
biological_process	GO:0097190	apoptotic signaling pathway	ISS
biological_process	GO:1900175	regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	NAS
biological_process	GO:1900180	regulation of protein localization to nucleus	IDA
biological_process	GO:1904339	negative regulation of dopaminergic neuron differentiation	IEA
biological_process	GO:1905327	tracheoesophageal septum formation	IEA
biological_process	GO:2000062	negative regulation of ureter smooth muscle cell differentiation	ISS
biological_process	GO:2000063	positive regulation of ureter smooth muscle cell differentiation	ISS
biological_process	GO:2000357	negative regulation of kidney smooth muscle cell differentiation	ISS
biological_process	GO:2000358	positive regulation of kidney smooth muscle cell differentiation	ISS
biological_process	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	ISS
biological_process	GO:2001054	negative regulation of mesenchymal cell apoptotic process	IEA
cellular_component	GO:0005576	extracellular region	TAS
cellular_component	GO:0005615	extracellular space	ISS
cellular_component	GO:0005788	endoplasmic reticulum lumen	TAS
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0005886	plasma membrane	TAS
cellular_component	GO:0009986	cell surface	ISS
cellular_component	GO:0045121	membrane raft	ISS
molecular_function	GO:0005113	patched binding	IDA
molecular_function	GO:0005509	calcium ion binding	IDA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005539	glycosaminoglycan binding	IEA
molecular_function	GO:0008233	peptidase activity	IEA
molecular_function	GO:0008270	zinc ion binding	IDA
molecular_function	GO:0016015	morphogen activity	TAS
molecular_function	GO:0043237	laminin-1 binding	ISS

Pathways (from Reactome)

Pathway description

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr