650


Homo sapiens (NCBI)

Features
Gene ID: 650
  
Biological name :
  
Synonyms : BDA2|BMP2A|SSFSC / BMP2 / bone morphogenetic protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205289_at (Human Genome U133 Plus 2.0 Array)   205290_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4557369
RefSeq - NC_000020.11
RefSeq - NG_023233.1
RefSeq - NP_001191.1
RefSeq - NM_001200.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000125845 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000187 activation of MAPK activity IDA
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0001649 osteoblast differentiation IDA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis ISS
 biological_processGO:0001666 response to hypoxia ISS
 biological_processGO:0001701 in utero embryonic development ISS
 biological_processGO:0001837 epithelial to mesenchymal transition IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0002062 chondrocyte differentiation IDA
 biological_processGO:0003130 BMP signaling pathway involved in heart induction IDA
 biological_processGO:0003181 atrioventricular valve morphogenesis ISS
 biological_processGO:0003203 endocardial cushion morphogenesis ISS
 biological_processGO:0003308 negative regulation of Wnt signaling pathway involved in heart development IDA
 biological_processGO:0006029 proteoglycan metabolic process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006954 inflammatory response ISS
 biological_processGO:0007219 Notch signaling pathway ISS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009887 animal organ morphogenesis ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IGI
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IDA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP
 biological_processGO:0010894 negative regulation of steroid biosynthetic process IDA
 biological_processGO:0010922 positive regulation of phosphatase activity IDA
 biological_processGO:0021537 telencephalon development IDA
 biological_processGO:0021978 telencephalon regionalization ISS
 biological_processGO:0030177 positive regulation of Wnt signaling pathway ISS
 biological_processGO:0030282 bone mineralization ISS
 biological_processGO:0030335 positive regulation of cell migration ISS
 biological_processGO:0030501 positive regulation of bone mineralization IDA
 biological_processGO:0030509 BMP signaling pathway TAS
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032092 positive regulation of protein binding IDA
 biological_processGO:0032348 negative regulation of aldosterone biosynthetic process IDA
 biological_processGO:0033690 positive regulation of osteoblast proliferation ISS
 biological_processGO:0035051 cardiocyte differentiation IMP
 biological_processGO:0035054 embryonic heart tube anterior/posterior pattern specification ISS
 biological_processGO:0035630 bone mineralization involved in bone maturation IDA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth ISS
 biological_processGO:0042482 positive regulation of odontogenesis ISS
 biological_processGO:0042487 regulation of odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway IDA
 biological_processGO:0045165 cell fate commitment ISS
 biological_processGO:0045600 positive regulation of fat cell differentiation ISS
 biological_processGO:0045666 positive regulation of neuron differentiation ISS
 biological_processGO:0045669 positive regulation of osteoblast differentiation IDA
 biological_processGO:0045778 positive regulation of ossification IDA
 biological_processGO:0045786 negative regulation of cell cycle IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048711 positive regulation of astrocyte differentiation ISS
 biological_processGO:0048762 mesenchymal cell differentiation IDA
 biological_processGO:0048839 inner ear development ISS
 biological_processGO:0051042 negative regulation of calcium-independent cell-cell adhesion IDA
 biological_processGO:0055007 cardiac muscle cell differentiation IMP
 biological_processGO:0055008 cardiac muscle tissue morphogenesis ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060039 pericardium development ISS
 biological_processGO:0060128 corticotropin hormone secreting cell differentiation ISS
 biological_processGO:0060129 thyroid-stimulating hormone-secreting cell differentiation ISS
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition IDA
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0060395 SMAD protein signal transduction IDA
 biological_processGO:0060485 mesenchyme development IMP
 biological_processGO:0060804 positive regulation of Wnt signaling pathway by BMP signaling pathway ISS
 biological_processGO:0061036 positive regulation of cartilage development IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071773 cellular response to BMP stimulus IMP
 biological_processGO:0072138 mesenchymal cell proliferation involved in ureteric bud development ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEP
 biological_processGO:1900745 positive regulation of p38MAPK cascade IDA
 biological_processGO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus IDA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:2000065 negative regulation of cortisol biosynthetic process IDA
 biological_processGO:2000726 negative regulation of cardiac muscle cell differentiation IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070724 BMP receptor complex IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity ISS
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0019211 phosphatase activator activity IDA
 molecular_functionGO:0039706 co-receptor binding IPI
 molecular_functionGO:0046332 SMAD binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0070700 BMP receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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